John Theurer Cancer Center Explained
John Theurer Cancer Center (JTCC) at the Hackensack University Medical Center (HUMC), and part of the Hackensack Meridian Health (HMH), specializes in oncology services and treatments.[1] It is known for being the first site approved to use cell-based gene therapy to treat patients with certain types of large B-cell lymphoma who have not responded or relapsed after at least two other kinds of treatment; it initiated the first CAR T-cell therapy clinical trials and is a member of the NCI-approved Georgetown Lombardi Comprehensive Cancer Center. Other areas of concentration include bone marrow transplants, stem cell transplantation, lymphoma, leukemia, multiple myeloma, neuro-oncology, cutaneous malignancy, gastrointestinal, geriatric, head and neck, thoracic, urologic, breast, and gynecologic.[2] As of 2023, Andre Goy is chair and Chief Physician Officer.[3] [4] [5]
Georgetown Lombardi Comprehensive Cancer Center affiliation
In 2019, JTCC received approval from the National Cancer Institute (NCI) as a member of the NCI-approved Georgetown Lombardi Comprehensive Cancer Center.[6] The partnership focuses on advancing research and treatment in breast cancer, cancer prevention and control, experimental therapeutics and molecular oncology.[7] [8] [9] The Georgetown Lombardi Comprehensive Center is designated by the National Cancer Institute as a leader in cancer treatment.[10]
Hackensack University Medical Center and Hackensack Meridian Health affiliations
JTCC is part of Hackensack University Medical Center. HUMC and part of the Hackensack Meridian Health network, which includes Joseph M. Sanzari Children's Hospital, the Cancer Center, a branch of The Betty Torricelli Institute for Breast Care, Ocean Medical Center, Pascack Valley Medical Center, and the Riverview Medical Center.[11] [12] [13]
In 2022, JTCC expanded its program to Hackensack Meridian Jersey Shore University Medical Center's HOPE Tower, providing access to specialized cancer services and access to clinical trials.[14]
Other affiliations
JTCC has a partnership with Memorial Sloan Kettering Cancer Center (MSK) to provide cancer care and develop joint standards of care through the oversight of a governing board composed of members from both MSK and HMH.[15]
In 2021, JTCC entered into a clinical affiliation with Regional Cancer Care Associates (RCCA) to open a practice called Toms River Regional Cancer Center in Toms River, NJ. The center provides comprehensive medical and surgical oncology/hematology consultative services by community-based, regional, and national specialists for various types and stages of cancer and serious blood disorders.[13]
In 2022, JTCC entered into a clinical affiliation with St. Joseph's Health to provide expanded cancer care services to the residents of Wayne, Paterson, and Totowa.
Green initiatives
In 2011, JTCC at HUMC opened a $130-million, 155,000-sq. ft. facility. The JTCC pavilion was built with a green roof, providing patients and visitors with a relaxing environment[16] and doubling as exterior insulation—greatly reducing heat gain and loss.[17] This reduces energy use for heating and cooling as well as harmful emissions.[18]
Notable accomplishments
- JTCC initiated the first CAR T-cell therapy clinical trials through its NCI collaboration and became the first certified center in New Jersey to offer this treatment, in which a patient's own immune cells (T-cells) are trained to fight cancer.[19]
- JTCC supports the Northeast's largest bone marrow transplant (BMT) program and, in 2014, performed 400 transplants.[8]
- Treated first US patient with an investigatory drug for relapsed glioblastoma and other anaplastic gliomas.[20] [21]
- First to use a biomarker surveillance program that screens patients who are at high-risk for developing pancreatic cancer.[22]
- Among the first of limited U.S. sites approved to offer Yescarta (axicabtagene ciloleucel), a cell-based gene therapy, to treat adult patients with certain types of large B-cell lymphoma who have not responded or relapsed after at least two other kinds of treatment.[23] As of 2023, it is also approved for all six commercially available CAR-T products for lymphoma, multiple myeloma and pediatric B-Cell precursor acute lymphoblastic leukemia: Yescarta, Tecartus (brexucabtagene autoleucel), Breyanzi (lisocabtagene maraleucel), Carvykti (ciltacabtagene autoleucel), Abecma (idecabtagene vicleucel), and Kymriah (tisagenlecleucel).
References
- Web site: Hackensack Meridian John Theurer Cancer Center . 2022-03-26.
- Web site: Hackensack, NJ . 2022-11-17 . Regional Cancer Care Associates . en-US.
- Goy . Andre . 2022-11-14 . Andre H. Goy, MD, on Unresolved Questions in Mantle Cell Lymphoma . Oncology . 36 . 11 . en . 651–653.
- Web site: Dr Andre Goy on Predictive Biomarker Use for CAR T-Cell Therapy Response in Patients With Large B-Cell Lymphoma . 2022-02-22 . AJMC . 12 December 2021 . en.
- Web site: Andre Goy, MD, Appointed Physician-in-Chief to Lead Cancer Care Across Hackensack Meridian Health Network . 2023-04-11 . OncLive . 18 June 2020 . en.
- Web site: 2019-05-10 . NCI approves Georgetown-Hackensack consortium . 2021-08-27 . The Cancer Letter . en-US.
- Web site: Vecchione . Anthony . 2019-05-07 . NCI approves John Theurer Cancer Center as research consortium member . 2021-08-27 . NJBIZ . en-US.
- Web site: NCI Approves John Theurer Cancer Center as Member of Research Consortium - The ASCO Post . 2021-08-27 . ascopost.com.
- Web site: Washburn . Lindy . New cancer treatment options in Passaic County from health system partnership . 2023-02-22 . North Jersey Media Group . en-US.
- Web site: 2012-07-26 . Georgetown Lombardi Comprehensive Cancer Center - NCI . 2023-03-22 . www.cancer.gov . en.
- Web site: Small numbers of cells in a tumor could be key enablers of cancer metastasis . 2022-02-22 . EurekAlert! . en.
- Web site: St. Joseph's Health and Hackensack Meridian Health: Affiliation Brings More Advanced Cancer Care To Northern New Jersey . 2023-03-04 . TAPinto . en.
- Web site: 2021-03-30 . Hackensack Meridian Health John Theurer Cancer Center (JTCC) creates affiliation with Regional Cancer Care Associates (RCCA) in Toms River, NJ . 2023-04-13 . Shore News Network . en-US.
- Web site: Ebenau . Vin. Jersey Shore University Medical Center now has expansive cancer care center with easier access for Ocean and Monmouth residents . 2023-04-11 . 92.7 WOBM . 3 May 2022 . en.
- Web site: Memorial Sloan Kettering and Hackensack Meridian Health . November 17, 2022 . Sloan Kettering.
- Web site: Psychological Benefit of Green Roofs . March 21, 2023 . Ohio.edu.
- Web site: Does a green roof have an insulating effect? - Sempergreen . 2023-03-21 . www.sempergreen.com.
- News: John Theurer Cancer Center at the Hackensack University Medical Center - Greenroofs.com . en-US . Greenroofs.com . 2022-11-17.
- Web site: John Theurer Cancer Center Recognized by US News & World Report . 2023-04-13 . New Jersey Business Magazine . en-US.
- Web site: Lindner . Linda . 2022-03-29 . John Theurer Cancer Center treats 1st patient in U.S. with investigational drug for brain cancer . 2022-11-17 . ROI-NJ . en-US.
- Tiek . Deanna M. . Erdogdu . Beril . Razaghi . Roham . Jin . Lu . Sadowski . Norah . Alamillo-Ferrer . Carla . Hogg . J. Robert . Haddad . Bassem R. . Drewry . David H. . Wells . Carrow I. . Pickett . Julie E. . Song . Xiao . Goenka . Anshika . Hu . Bo . Goldlust . Samuel A. . 2022-06-24 . Temozolomide-induced guanine mutations create exploitable vulnerabilities of guanine-rich DNA and RNA regions in drug-resistant gliomas . Science Advances . en . 8 . 25 . eabn3471 . 10.1126/sciadv.abn3471 . 2375-2548 . 9216507 . 35731869. 2022SciA....8N3471T .
- Web site: NJBIZ . 2022-04-28 . Hackensack UMC unveils new pancreatic cancer test . 2022-11-17 . NJBIZ . en-US.
- Web site: John Theurer Cancer Center First NJ Site Certified to offer CAR-T Cell Cancer Therapy . 2022-11-17 . OncLive . 9 March 2018 . en.
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