| John St John | |
| Office1: | High Sheriff of Bedfordshire and Buckinghamshire |
| Term1: | 1529-1530 1534-1535 1549-1550 |
| Office2: | Member of Parliament for Bedfordshire |
| Term2: | c. 1529? 1539 1542 |
| Birth Date: | By 1495 |
| Spouse: | Anne Neville |
| Children: | 14, including Oliver |
| Relatives: | John St John (grandson) Oliver St John (grandson) |
Sir John St John (by 1495 – 19 December 1558), of Bletsoe, Bedfordshire, was an English politician.
He was the son of Sir John St John of Bletsoe and his wife Sybil, daughter of Rhys ap Morgan. He succeeded his father in 1525 and was knighted the following year.
He was High Sheriff of Bedfordshire and Buckinghamshire for 1529–30, 1534–35, and 1549–50. He was a Member (MP) of the Parliament of England for Bedfordshire in 1529?, 1539 and 1542.[1]
He first married, in 1521, Margaret, the daughter of Sir William Waldegrave of Smallbridge, Suffolk, with whom he had 5 sons (including John and Oliver) and 4 daughters and secondly Anne, the daughter of Thomas Neville of Cotterstock, Northamptonshire, with whom he had a further son and four daughters.