| John Sefa Kwadwo Ayim | |
| Vice Chancellor of the Kwame Nkrumah University of Science and Technology | |
| Term Start: | September 1999 |
| Term End: | September 2002 |
| Predecessor: | E. H. Amonoo-Neizer |
| Successor: | Kwesi Akwansah Andam |
| Alma Mater: | University of London (Ph.D) 1973. Kwame Nkrumah University of Science and Technology (B.Pharm) |
| Profession: | Pharmacist, Professor |
| Spouse: | Grace Sefah Ayim |
| Children: | 3 |
John Sefa Ayim is a Ghanaian academician and the former Vice Chancellor of the Kwame Nkrumah University of Science and Technology.[1] He is the first Alumnus of Kwame Nkrumah University of Science and Technology to become a Vice Chancellor. He was the Dean of the Faculty of Pharmacy (1996 to 1999), Head of the Department of Pharmaceutical Chemistry, of the Kwame Nkrumah University of Science and Technology.
Ayim served as Vice Chancellor of KNUST from 1999 to 2002.[1]