| State Senate: | Mississippi |
| District: | 16th |
| Birth Date: | 10 March 1854 |
| Birth Place: | Gainesville, Alabama |
| Termstart: | January 1916 |
| Termend: | January 1920 |
| Party: | Democrat |
| Death Place: | Macon, Mississippi |
John Quarles Poindexter (March 10, 1854 – September 17, 1932) was a Democratic member of the Mississippi State Senate, representing the 16th district, from 1916 to 1920.
John Quarles Poindexter was born on March 10, 1854, in Gainesville, Alabama.[1] He was the son of William Rice Poindexter and Martha Jane (Barrett) Poindexter. After the death of his father in 1870, John attended Reagan High School in Morristown, Tennessee. He became a planter and merchant. He became a member of the Mississippi State Senate in 1916, representing the 16th district as a Democrat.[2] He served from 1916 to 1920. He died at his home in Macon after a long illness on September 17, 1932.[3] He was survived by his widow and four children.
He was a Presbyterian. He married Lucinda George Richards in 1878. They had four children, all of whom survived John.