John Philip Trinkaus Explained
John Philip "Trink" Trinkaus (23 May 1918, Rockville Centre, New York – 8 February 2003, Guilford, Connecticut) was an American embryologist and one of the world's leading experts on in vivo cell motility.[1] [2]
Biography
Trinkaus graduated in 1940 with a B.A. in biology from Wesleyan University[3] and in 1941 with an M.A. from Columbia University. In 1941 he matriculated at Johns Hopkins University, but WW II interrupted his graduate study.[4] In August 1942 he was drafted into the U.S. Army. In the spring of 1943 he went on leave for a week to marry Galina Gorokhoff, whom he had met a few years earlier at the Marine Biological Laboratory in Woods Hole. After being stationed in the United States and training U.S. Army Air Force officers in the use of oxygen equipment, he was sent to Italy in the autumn of 1944 to train officers in the use of G-suits. He was discharged from the U.S. Army in December 1945.[5] In 1948 he graduated with a Ph.D. in embryology from Johns Hopkins University.[4]
In 1948 Trinkaus became an instructor in Yale University's department of zoology (which later became the department of biology). He was soon promoted to full professor, retaining that position until he retired as professor emeritus. With few exceptions, he spent his summers at the Marine Biological Laboratory in Woods Hole.[4] For the academic year 1959–1960 he was a Guggenheim Fellow at the Collège de France.[4] During that year he met the woman, Madeleine Robineaux, who was to become his second wife. After divorcing their spouses, they married in October 1963. His 1969 book Cells into Organs. The Forces That Shape the Embryo became a classic treatise on cell and tissue movement during embryonic development[1] [6] and cell invasion of bodily tissues.[4] A greatly enlarged 2nd edition was published in 1984.[7]
Trinkaus was a member of NASA's U.S. Space Biology Advisory Panel from 1976 to 1979.[4] He was the author or co-author of about 50 scientific articles during his career. His autobiography was published posthumously in 2004.[8] [9]
Awards and honors
- 1959 — Guggenheim Fellowship[10]
- 1995 — Edward Grant Conklin Medal from the Society of Developmental Biology.[1]
- 1988 — "Trinkfest" (a Festschrift or retirement party) held by the Marine Biological Laboratory in celebration of Trinkaus's 70th birthday[11]
Selected publications
- Trinkaus. J. P.. The Surface Gel Layer of Fundulus Eggs in Relation to Epiboly. Proceedings of the National Academy of Sciences. 35. 4. 1949. 218–225. 0027-8424. 10.1073/pnas.35.4.218. 16588888. 1063003. 1949PNAS...35..218T. free.
- 10.1002/jez.1401180204. A study of the mechanism of epiboly in the egg of Fundulus heteroclitus. 1951. Trinkaus. J. P.. Journal of Experimental Zoology. 118. 2. 269–319.
- 10.1073/pnas.41.10.787. Differentiation in Culture of Mixed Aggregates of Dissociated Tissue Cells. 1955. Trinkaus. J. P.. Groves. P. W.. Proceedings of the National Academy of Sciences. 41. 10. 787–795. 16589751. 528186. 1955PNAS...41..787T. free .
- Movements of Epithelial Cell Sheets in Vitro. Journal of Cell Science. December 1966. 1. 4. 407–413. Trinkaus. J. P.. Vaughan. R. B.. 10.1242/jcs.1.4.407. 5956715.
- 10.1083/jcb.44.3.592. Electrical Coupling Between Embryonic Cells by Way of Extracellular Space and Specialized Junctions. 1970. Bennett. M. V. L.. Trinkaus. J. P.. The Journal of Cell Biology. 44. 3. 592–610. 5415239. 2107981. free.
- 10.1083/jcb.48.3.455. Differentiation of the Junctional Complex of Surface Cells in the Developing Fundulus Blastoderm. 1971. Lentz. Thomas L.. Trinkaus. J. P.. The Journal of Cell Biology. 48. 3. 455–472. 5545331. 2108114.
- Surface activity and locomotion of Fundulus deep cells during blastula and gastrula stages. 10.1016/0012-1606(73)90049-3. 1973. Trinkaus. J.P.. Developmental Biology. 30. 1. 68–103. 4735370.
- 10.1016/0014-4827(76)90595-4. Microvilli and blebs as sources of reserve surface membrane during cell spreading. 1976. Erickson. C.A.. Trinkaus. J.P.. Experimental Cell Research. 99. 2. 375–384. 1269533.
- 10.1002/jez.1402060310. Contact relations, surface activity, and cortical microfilaments of marginal cells of the enveloping layer and of the yolk syncytial and yolk cytoplasmic layers of Fundulus before and during epiboly. 1978. Betchaku. T.. Trinkaus. J. P.. Journal of Experimental Zoology. 206. 3. 381–426. 568653.
- Trinkaus. J. P.. Mechanism of Fundulus Epiboly—A Current View. American Zoologist. 24. 3. 1984. 673–688. 0003-1569. 10.1093/icb/24.3.673. free.
- 10.1016/0012-1606(87)90099-6. Rearrangement of enveloping layer cells without disruption of the epithelial permeability barrier as a factor in Fundulus epiboly. 1987. Keller. R.E.. Trinkaus. J.P.. Developmental Biology. 120. 1. 12–24. 3817284.
References
- John P. Trinkaus. Society for Developmental Biology (sdbonline.org).
- Yale News. In Memoriam: World Renowned Developmental Biologist at Yale, John P. Trinkaus. February 14, 2003.
- Web site: John Philip Trinkaus – Trink's Undergraduate Research at Wesleyan University. History of the Marine Biological Laboratory.
- DuPont, Ellen M.. John Philip Trinkaus (1918-2003). Embryo Project Encyclopedia. 2010-05-31. 1940-5030. Arizona State University. School of Life Sciences. Center for Biology and Society..
- Book: Trinkaus, J. P.. Chapter 3. Graduate Studies and the War. Embryologist (autobiography).
- Jacobson. A.. Review of Cells into Organs. The Forces That Shape the Embryo by J. P. Trinkaus. Science. 168. 3929. 1970. 356. 0036-8075. 10.1126/science.168.3929.356-a.
- 10.1086/414213. Review of Cells into Organs. The Forces That Shape the Embryo by John Philip Trinkaus. 1985. Pierce. Michael. The Quarterly Review of Biology. 60. 79–80.
- 10.1086/421612. Review of Embryologist: My Eight Decades in Developmental Biology. 2004. Harris. Albert K.. The Quarterly Review of Biology. 79. 78.
- 10.1002/dvdy.10423. Trink: His life, his philosophy (review of Embryologist: My Eight Decades in Developmental Biology by John Philip Trinkaus). 2003. Schoenwolf. Gary C.. Developmental Dynamics. 228. 4. 591–593. free.
- Web site: John Philip Trinkaus. John Simon Guggenheim Memorial Foundation.
- Web site: History of the Marine Biology Laboratory. John Philip Trinkaus - Conclusion.
External links