| John McGuinness | |
| Position: | First baseman |
| Bats: | Unknown |
| Throws: | Unknown |
| Birth Date: | 1857 |
| Birth Place: | Ireland |
| Death Place: | Binghamton, New York |
| Debutleague: | MLB |
| Debutdate: | May 6 |
| Debutyear: | 1876 |
| Debutteam: | New York Mutuals |
| Finalleague: | MLB |
| Finaldate: | August 7 |
| Finalyear: | 1884 |
| Finalteam: | Philadelphia Keystones |
| Statleague: | MLB |
| Stat1label: | Batting average |
| Stat1value: | .244 |
| Stat2label: | Home runs |
| Stat2value: | 0 |
| Stat3label: | Runs scored |
| Stat3value: | 32 |
| Teams: |
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John James McGuinness (1857 – December 19, 1916) was an Irish professional baseball player. He played in three seasons in Major League Baseball, 1876 for the New York Mutuals, 1879 for the Syracuse Stars, and 1884 for the Philadelphia Keystones of the Union Association. He was mostly used as a first baseman.