| John Muiruri | |
| Fullname: | John Machethe Muiruri |
| Birth Date: | 10 October 1979 |
| Birth Place: | Kenya |
| Currentclub: | Moss FK |
| Clubnumber: | 4 |
| Position: | Midfielder |
| Years1: | 1998–1999 |
| Years2: | 1999–2000 |
| Years3: | 2001–2004 |
| Years4: | 2004–2005 |
| Years5: | 2005– |
| Clubs1: | Utalii |
| Clubs2: | Tusker |
| Clubs3: | Gent |
| Clubs4: | Germinal Beerschot |
| Clubs5: | Moss |
| Caps3: | 48 |
| Caps4: | 30 |
| Caps5: | 111 |
| Goals3: | 4 |
| Goals4: | 0 |
| Goals5: | 21 |
| Nationalyears1: | 1998–2007 |
| Nationalteam1: | Kenya |
| Nationalcaps1: | 23 |
| Nationalgoals1: | 1 |
| Pcupdate: | 22:57, 27 November 2009 (AEST) |
| Ntupdate: | 27 November 2009 |
John Machethe "Mo" Muiruri (born 10 October 1979) is a Kenyan footballer who played for Moss FK in Norway as a midfielder. He was known for his close ball control and ability to dribble the ball. He is one of the most talented midfield quartet of the Kenya National team, Harrambe Stars along with McDonald Mariga, Robert Mambo, Jamal Mohamed and Titus Mulama. He led Kisii School to two national championships before graduating in 1997.
Muiruri has played 20 international matches for Kenya as well as 13 matches at U-21 and U-23 level. He appeared at the 2004 African Cup of Nations.