| John Lyston | |
| Position: | Pitcher |
| Birth Date: | 28 May 1867 |
| Birth Place: | Baltimore, Maryland |
| Death Place: | Baltimore, Maryland |
| Bats: | Right |
| Throws: | Right |
| Debutleague: | MLB |
| Debutdate: | August 29 |
| Debutyear: | 1891 |
| Debutteam: | Columbus Solons |
| Finalleague: | MLB |
| Finaldate: | June 15 |
| Finalyear: | 1894 |
| Finalteam: | Cleveland Spiders |
| Statleague: | MLB |
| Stat1label: | Win–loss record |
| Stat1value: | 0–1 |
| Stat2label: | Earned run average |
| Stat2value: | 10.24 |
| Stat3label: | Strikeouts |
| Stat3value: | 1 |
| Teams: | |
John Michael Lyston (May 28, 1867 - October 29, 1909) was an American professional baseball player who played in one game for the Columbus Solons during the season and one game for the Cleveland Spiders during the season. He was born in Baltimore, Maryland, and died there at the age of 42.