| John II | |
| Succession: | Duke of Calabria |
| Reign: | 1435–1470 |
| Predecessor: | René of Anjou |
| Successor: | Nicholas I, Duke of Lorraine |
| Birth Date: | 2 August 1426 |
| Birth Place: | Nancy |
| Death Place: | Barcelona |
| Spouse: | Marie de Bourbon |
| Issue: | Isabelle Jean René Marie Nicholas I, Duke of Lorraine John Albert Jeanne d'Abancourt Marguerite Daughter |
| House: | Anjou |
| Father: | René, King of Naples |
| Mother: | Isabella, Duchess of Lorraine |
| Succession1: | Duke of Lorraine |
| Reign1: | 1453–1470 |
| Predecessor1: | Isabella and René of Anjou |
| Successor1: | Nicholas I, Duke of Lorraine |
| Succession2: | Prince of Girona (Claimant) |
| Reign2: | 1466–1470 |
| Predecessor2: | Charles, Prince of Viana |
| Successor2: | Ferdinand II of Aragon |
John II of Anjou (Nancy, August 2, 1426 - December 16, 1470, Barcelona) was Duke of Lorraine from 1453 to his death. He was the son of René of Anjou and Isabella, Duchess of Lorraine. He was married to Marie de Bourbon, daughter of Charles I, Duke of Bourbon.
John inherited the duchy from his mother, Duchess Isabelle, during the life of his father, Duke René of Anjou, also Duke of Lorraine and titular king of Naples. As heir-apparent of Naples, he was styled the Duke of Calabria and spent most of his time engaging in plots for the Angevin recovery of Naples. In 1460, he decisively defeated the king of Naples Ferdinand at Nola, but was unable to prevent others from coming to his aid. He was defeated at Troia in 1462 and at Ischia in 1465. In 1466, the Catalans chose his father as King of Aragon, and he was created Prince of Girona, as heir-apparent. He went into Catalonia to press the family's claims, but died, supposedly by poison, in Barcelona.
In 1444, he married Marie de Bourbon (1428–1448), daughter of Charles I, Duke of Bourbon and Agnes of Burgundy, Duchess of Bourbon (and granddaughter to John the Fearless, and niece to Philip the Good, both Dukes of Burgundy and enemies and allies to her father). Marie was from the House of Bourbon and was the only Duchess consort of Lorraine from the reign of Valois-Anjou. The marriage contract was signed in April 1437, however, the ceremony took place around 1444 when she was older and would be able to consummate the marriage.Marie and John had the following issue:
Marie died giving birth to her last and only surviving child Nicholas; she died on July 7, 1448, and was buried at Meurthe-et-Moselle Lorraine, France.
John also had several illegitimate children:
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