| John I, Lord of Ligny | |
| Succession: | Lord of Ligny, La Roche, Beauvoir and Roussy |
| Reign: | 1354–1364 |
| Predecessor: | Waleran II |
| Successor: | Guy I |
| House: | Luxembourg |
| Father: | Waleran II of Luxembourg, Lord of Ligny |
| Mother: | Guyotte of Lille |
| Spouse: | Alix of Dampierre |
| Issue: | Marie of Luxembourg John, Lord of Roussy Guy I, Count of Ligny John, Archbishop of Strasbourg Johanna of Luxembourg |
| Birth Date: | 1313 |
| Death Date: | 17 May |
John I of Luxembourg (French: Jean I<sup>er</sup> de Luxembourg; died: 17 May 1364), was a Lord of Ligny, Beauvoir, Roussy and La Roche from the House of Luxembourg. He was a son of Lord Waleran II and his wife, Guyotte of Lille. He was a 3rd generation descendant of Henry V, Count of Luxembourg.
Around 1330 he married Alix of Dampierre (d. 1346), the heiress of Guy of Dampierre-Richebourg. Their children were: