| John Guier Scott | |
| Image Name: | JohnGuierScott.jpg |
| State2: | Missouri |
| District2: | 3rd |
| Term Start2: | December 7, 1863 |
| Term End2: | March 3, 1865 |
| Preceded2: | John William Noell |
| Succeeded3: | Thomas E. Noell |
| Birth Date: | 26 December 1819 |
| Birth Place: | Philadelphia, Pennsylvania |
| Death Place: | Oliver Springs, Tennessee |
| Party: | Democratic |
John Guier Scott (December 26, 1819 – May 16, 1892) was a U.S. Representative from Missouri.
Born in Philadelphia, Pennsylvania, Scott completed preparatory studies.He was graduated from Bethlehem Academy, Pennsylvania, in civil engineering.He moved to Missouri in 1842.He served as general manager of the Iron Mountain Co. at Iron Mountain.He established the Irondale Iron Co. at Irondale in 1858.He was an unsuccessful Democratic candidate for election in 1862 to the Thirty-eighth Congress.
Scott was subsequently elected as a Democrat to the Thirty-eighth Congress to fill the vacancy caused by the death of John W. Noell and served from December 7, 1863, to March 3, 1865.He engaged in the drug business in St. Louis.
He resumed mining, and built furnaces, at Scotia, Missouri, in 1868 and at Nova Scotia a year later.He returned in 1870 to St. Louis.He moved to east Tennessee about 1880.
He died at Oliver Springs, Tennessee, on May 16, 1892, and was interred at Bellefontaine Cemetery in St. Louis, Missouri.