John Burn (geneticist) explained

Sir John Burn
Birth Date:1952 2, df=y
Fields:Cancer
Genetics
Workplaces:Newcastle University
Great Ormond Street Hospital
Royal Victoria Infirmary
Education:Barnard Castle Grammar School
Alma Mater:Newcastle University (MB BS, MD)
Thesis Title:Cardiovascular malformation : an analysis of genetic contribution
Thesis Url:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.241347
Thesis Year:1991
Known For:Centre for Life
Human Variome Project
Awards:Knight Bachelor (2010)

Professor Sir John Burn (born 6 February 1952) is a British professor of Clinical Genetics at Newcastle University and senior leader in England's National Health Service.[1] [2]

Education

Burn was born and raised in the North East of England. He was educated at Barnard Castle Grammar School, (now Teesdale School) and Newcastle University Medical School from 1976 to 1980 where he was awarded a Bachelor of Medical Sciences (BMedSci) degree in 1973, a Bachelor of Medicine, Bachelor of Surgery (MB BS) in 1976 and a Doctor of Medicine (MD) degree in 1991.[3]

Career and research

Burn has been Professor of Clinical Genetics at Newcastle University since 1991 and a consultant specialist since 1984.[4] He is a recognised authority on the genetics of cancer.[5] [6] [7] He led the regional NHS Genetics Service for 20 years and helped to create the Centre for Life which houses an education and science centre alongside the Institute of Genetic Medicine[4] and Northgene Ltd,[8] the identity testing company he launched in 1995. He chairs DNA device company QuantuMDx.[9]

Between 2014 and 2018, he was a non-executive director of NHS England.[10] [11] In 2016, he was appointed Executive Chairman of Global Variome Ltd, a not-for-profit company supporting services to the international coordination work of the Human Variome Project.[12] [13] [14]

In 2017, he became Chair of Newcastle upon Tyne Hospitals NHS Foundation Trust.[15] His term as chair of the trust ended in 2024, and was taken over by Professor Kath McCourt.[16]

Awards and honours

In 2010, Burn was appointed Knight Bachelor by Her Majesty Queen Elizabeth II for outstanding services to medicine.[17]

He was chosen as one of the first 20 ‘local heroes’ to be commemorated with a brass plaque on Newcastle Quayside in 2014, and the following year, he received the Living North award for services to the North East 2000 – 2015.[18] [19]

The Harveian Oration 2019 was delivered by Burn, his lecture ‘Prediction and prevention in the genomic era’, outlined the history of genetic medicine, presented the challenges in using genetics to predict medical conditions and explained how he looks forward to seeing if we can use its full potential to prevent disease in the future.[20]

In 2020, Burn was selected as the incumbent of the 2020 Niehaus, Southworth, Weissenbach Award and Visiting Professorship in Clinical Cancer Genetics at Memorial Sloan Kettering Cancer Center. The award recognises leaders in the translation of germline genetics to preventive care of cancer patients and their families. Due to COVID-19 restrictions, Burn did not receive his award and present his lecture until May 2021.

Media interest

He was interviewed by Jim Al-Khalili for The Life Scientific on Radio 4 first broadcast in February 2018.[21]

Burn's daughter, son in law and grandkids earned national fame since the first lockdown in 2020 with a series of entertaining and quirky cover versions performed in their front room. The family surprised Burn with their Prostatectomy song, in homage to the successful operation he had to remove his prostate.[22]

Notes and References

  1. http://www.debretts.com/people/biographies/browse/b/11042/John+BURN.aspx John Burn in Debretts
  2. Burn . John . John Burn (geneticist). 10.1136/bmj.f3133 . Should we sequence everyone's genome? Yes . BMJ . 346 . f3133 . 2013 . 23694691. 206898051 .
  3. MD. University of Newcastle upon Tyne. Cardiovascular malformation : an analysis of genetic contribution. John. Burn. 1991. . copac.jisc.ac.uk. 24724804. 2018-02-18. https://web.archive.org/web/20180219150739/http://copac.jisc.ac.uk/id/18918596?style=html. 2018-02-19. dead.
  4. Web site: Staff Profile - Institute of Genetic Medicine - Newcastle University. www.ncl.ac.uk. 2017-04-26. 2017-04-27. https://web.archive.org/web/20170427003717/http://www.ncl.ac.uk/igm/staff/profile/johnburn.html. dead.
  5. Bertagnolli. Monica M.. Eagle. Craig J.. Zauber. Ann G.. Ann Zauber . Redston. Mark. Solomon. Scott D.. Kim. KyungMann. Tang. Jie. Rosenstein. Rebecca B.. Wittes. Janet. Janet Wittes. Corle. Donald. Hess. Timothy M.. Woloj. G. Mabel. Boisserie. Frédéric. Anderson. William F.. Viner. Jaye L.. Bagheri. Donya. Burn. John. Chung. Daniel C.. Dewar. Thomas. Foley. T. Raymond. Hoffman. Neville. Macrae. Finlay. Pruitt. Ronald E.. Saltzman. John R.. Salzberg. Bruce. Sylwestrowicz. Thomas. Gordon. Gary B.. Hawk. Ernest T.. Celecoxib for the Prevention of Sporadic Colorectal Adenomas. New England Journal of Medicine. 355. 9. 2006. 873–884. 0028-4793. 10.1056/NEJMoa061355. 16943400. free.
  6. Dunlop. M.. Cancer risk associated with germline DNA mismatch repair gene mutations. Human Molecular Genetics. 6. 1. 1997. 105–110. 1460-2083. 10.1093/hmg/6.1.105. 9002677. free.
  7. Burn. John. Gerdes. Anne-Marie. Macrae. Finlay. Mecklin. Jukka-Pekka. Moeslein. Gabriela. Olschwang. Sylviane. Eccles. Diane. Evans. D Gareth. Maher. Eamonn R. Bertario. Lucio. Bisgaard. Marie-Luise. Dunlop. Malcolm G. Ho. Judy WC. Hodgson. Shirley V. Lindblom. Annika. Lubinski. Jan. Morrison. Patrick J. Murday. Victoria. Ramesar. Raj. Side. Lucy. Scott. Rodney J. Thomas. Huw JW. Vasen. Hans F. Barker. Gail. Crawford. Gillian. Elliott. Faye. Movahedi. Mohammad. Pylvanainen. Kirsi. Wijnen. Juul T. Fodde. Riccardo. Lynch. Henry T. Mathers. John C. Bishop. D Timothy. Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial. The Lancet. 378. 9809. 2011. 2081–2087. 0140-6736. 10.1016/S0140-6736(11)61049-0. 22036019. 3243929.
  8. Web site: NorthGene – DNA Testing You Can Be Sure Of. NorthGene.
  9. Web site: QuantuMDx - Molecular Diagnostics in Minutes. quantumdx.com.
  10. Web site: QuantuMDx CMO Prof Sir John Burn Appointed To NHS Board Of Directors. 2020-10-12. BioSpace. en-US.
  11. Web site: NHS England » NHS England Annual Report 2018/19. 2020-10-12. www.england.nhs.uk.
  12. Web site: John BURN - Personal Appointments (free information from Companies House). 2020-10-12. find-and-update.company-information.service.gov.uk. en.
  13. Burn. John. Watson. Michael. The Human Variome Project. Human Mutation. 37. 6. 2016. 505–507. 1059-7794. 10.1002/humu.22986. 26987309. free.
  14. Web site: Human Variome Project. www.humanvariomeproject.org.
  15. Web site: Dickinson. Katie. 2017-11-16. Newcastle's NHS trust announces appointment of new chairman. 2020-10-12. ChronicleLive.
  16. Web site: Volpe . Sam . 2024-03-04 . Newcastle Hospitals NHS Trust announces new leaders as it looks to rebuild . 2024-04-07 . Chronicle Live . en.
  17. News: Knighthood for leading geneticist. 31 December 2009. news.bbc.co.uk.
  18. Web site: Prof Sir John Burn - NewcastleGateshead. www.newcastlegateshead.com.
  19. Web site: Renowned academic recognised for his contribution to the North East. 7 December 2015. 26 April 2017. https://web.archive.org/web/20170427003714/http://www.ncl.ac.uk/press/news/2015/12/sirjohnburnlivingnorthaward/. 27 April 2017. dead.
  20. Web site: 2019-04-02. Harveian Oration and Dinner 2019. 2022-01-17. RCP London.
  21. Web site: Al-Khalili. Jim. 2018. John Burn and the genetics of cancer. bbc.co.uk. BBC. London.
  22. Web site: The Marsh Family presents Prostate cancer – The Facts Of Life. 2022-01-17. Prostate Cancer UK. en.

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