| Birth Date: | 21 December 1841 |
| Birth Place: | Clarke County, Georgia |
| Death Place: | Tallahassee, Florida |
| Spouse: | Mary Turman Mattie Ward |
| Children: | Flora Waldo John Ward Henderson Mary Henderson Jennie Murphree |
| Party: | Democratic |
| Relations: | W. B. Henderson (brother) |
| Occupation: | Lawyer |
| Office: | Mayor of Tampa |
| Rank: | 2nd Lieutenant |
| Unit: | 7th Florida Infantry, Co. B |
| Battles: | American Civil War |
| Serviceyears: | 1862 |
John Alexander Henderson (December 21, 1841 - August 10, 1904) was a corporate lawyer and politician in Florida. He was an early resident of Tampa, the brother of William Benton Henderson.[1] He studied law under James Gettis, who raised him after the death of his father. During the Civil War, Henderson was in Gettis's company. He was elected mayor of Tampa in 1870.[2]
In 1876, he moved to Tallahassee.[3] His second wife was the daughter of G. T. Ward.[4] He served as general consul for the Florida Central & Peninsular Railroad Company.[5] He was a trustee of the West Florida Seminary, and his daughter Jennie married Albert A. Murphree.[6] He taught law to William Himes.[7] He was a state senator. William D. Bloxham appointed him a US Senator when Wilkinson Call's term expired.[8]