| Joe Santone | |
| Position: | Guard |
| Birth Date: | 1 October 1893 |
| Birth Place: | Campobasso, Italy |
| Death Place: | Hartford, Connecticut, U.S. |
| Weight Lbs: | 180 |
| College: | None |
| Pastteams: | |
| Statlabel1: | Games played |
| Statvalue1: | 2 |
| Pfr: | SantJo20 |
Joseph Santone (October 1, 1893 – October 27, 1963) was an Italian professional American football guard who played one season for the Hartford Blues of the National Football League (NFL). Santone made two appearances.
Santone was born on October 1, 1893, in Campobasso, Italy. His high school is unknown. Santone did not attend college. In 1926, he made two appearances for the Hartford Blues of the National Football League (NFL) as a guard.[1] His weight was listed at 180, but his height is unknown.[2] He did not make any more appearances after the season as the Blues folded from the league.[3] He later lived in Hartford, Connecticut, and died there on October 27, 1963, at the age of 70.[4]