Joe M. McCord explained

Joe Milton McCord
Citizenship:United States
Field:Biochemistry
Work Institution:University of Colorado
Alma Mater:Rhodes College, Duke University
Doctoral Advisor:Irwin Fridovich
Known For:Discovery of superoxide dismutase

Joe Milton McCord (born March 3, 1945) is an American biochemist. While serving as a graduate student, he and his supervisor Irwin Fridovich were the first to describe the enzymatic activity of superoxide dismutase.[1] [2] McCord joined the board of directors of the LifeVantage Corporation (makers of the dietary supplement Protandim) in 2006, serving as the company's chief science officer from 2011 to 2012, and retired from the company in June 2013.[3]

Academic background

McCord received a B.S. degree in chemistry from Rhodes College (graduated 1966) and a Ph.D. in biochemistry from Duke University (graduated 1970), where he also conducted postdoctoral research.

McCord is a past recipient of the Discovery Award from the Society for Free Radical Biology and Medicine (shared with Irwin Fridovich),[4] the Elliott Cresson Medal, and a Lifetime Achievement Award from the Oxygen Society.

LifeVantage/Protandim

McCord served on the board of directors (Director of Science) of the LifeVantage Corporation beginning in 2006 and was listed by the SEC as an insider shareholder.[5] LifeVantage is a Utah-based multilevel marketing company that distributes an antioxidant dietary supplement known as Protandim. McCord co-authored 7 studies on the product[6] [7] [8] [9] [10] [11] [12] and participated in distributor training.[5] McCord served as chief scientific officer for LifeVantage from June 2011 until September 2012, and then became a member of the company's science advisory board. LifeVantage announced McCord's retirement in June 2013.[3] [13] Under the terms of the separation agreement, McCord was to receive a payment of $1.7 million from the company.[13]

Pathways Bio

McCord co-founded Pathways Bioscience to improve health span and overcome health and wellness problems associated with aging by supporting the body's own defense mechanisms that allow it to protect and heal itself. Pathways Bioscience is focused on the discovery and development of new agents that regulate gene expression and exert beneficial effects by influencing cell defense pathways.[14]

External links

Notes and References

  1. McCord JM, Fridovich I . Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein) . J. Biol. Chem. . 244 . 22 . 6049–55 . November 1969 . 10.1016/S0021-9258(18)63504-5 . 5389100. free .
  2. Keele BB, McCord JM, Fridovich I . Superoxide dismutase from escherichia coli B. A new manganese-containing enzyme . J. Biol. Chem. . 245 . 22 . 6176–81 . November 1970 . 10.1016/S0021-9258(18)62675-4 . 4921969. free .
  3. Web site: Corporation . Lifevantage . Dr. Joe McCord, LifeVantage Corporation's First Chief Science Officer, Retires From Company . GlobeNewswire News Room . 25 June 2013 . 19 April 2021.
  4. Web site: SFRBM - Society for Free Radical Biology and Medicine .
  5. http://secwatch.com/mccord-joe-m{{full citation needed|date=July 2013}}
  6. Nelson SK, Bose SK, Grunwald GK, Myhill P, McCord JM . The induction of human superoxide dismutase and catalase in vivo: a fundamentally new approach to antioxidant therapy . Free Radic. Biol. Med. . 40 . 2 . 341–7 . January 2006 . 16413416 . 10.1016/j.freeradbiomed.2005.08.043.
  7. Velmurugan K, Alam J, McCord JM, Pugazhenthi S . Synergistic induction of heme oxygenase-1 by the components of the antioxidant supplement Protandim . Free Radic. Biol. Med. . 46 . 3 . 430–40 . February 2009 . 19056485 . 10.1016/j.freeradbiomed.2008.10.050.
  8. Liu J, Gu X, Robbins D, etal . Protandim, a fundamentally new antioxidant approach in chemoprevention using mouse two-stage skin carcinogenesis as a model . PLOS ONE . 4 . 4 . e5284 . 2009 . 19384424 . 2668769 . 10.1371/journal.pone.0005284. 2009PLoSO...4.5284L . free .
  9. Robbins D, Gu X, Shi R, etal . The chemopreventive effects of Protandim: modulation of p53 mitochondrial translocation and apoptosis during skin carcinogenesis . PLOS ONE . 5 . 7 . e11902 . 2010 . 20689586 . 2912769 . 10.1371/journal.pone.0011902. 2010PLoSO...511902R . free .
  10. Bogaard HJ, Natarajan R, Henderson SC, etal . Chronic pulmonary artery pressure elevation is insufficient to explain right heart failure . Circulation . 120 . 20 . 1951–60 . November 2009 . 19884466 . 10.1161/CIRCULATIONAHA.109.883843. free .
  11. Qureshi MM, McClure WC, Arevalo NL, etal . The Dietary Supplement Protandim Decreases Plasma Osteopontin and Improves Markers of Oxidative Stress in Muscular Dystrophy Mdx Mice . J Diet Suppl . 7 . 2 . 159–178 . June 2010 . 20740052 . 2926985 . 10.3109/19390211.2010.482041.
  12. Joddar B, Reen RK, Firstenberg MS, etal . Protandim attenuates intimal hyperplasia in human saphenous veins cultured ex vivo via a catalase-dependent pathway . Free Radic. Biol. Med. . 50 . 6 . 700–9 . March 2011 . 21167278 . 10.1016/j.freeradbiomed.2010.12.008.
  13. News: Form 8-K for LifeVantage Corp. November 10, 2013. Yahoo.com. June 25, 2013.
  14. https://www.pathwaysbio.com/

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