| Joe DePre | |
| Birth Date: | 19 December 1947 |
| Birth Place: | Westbury, New York |
| Nationality: | American |
| Height Ft: | 6 |
| Height In: | 3 |
| Weight Lb: | 185 |
| High School: | Westbury (Westbury, New York) |
| College: | St. John's (1967–1970) |
| Draft Year: | 1970 |
| Draft Round: | 2 |
| Draft Pick: | 29 |
| Draft Team: | Phoenix Suns |
| Career Position: | Shooting guard |
| Career Number: | 21 |
| Years1: | 1970–1972 |
| Team1: | New York Nets |
| Bbr: | deprejo01 |
Joe DePre (born December 19, 1947) is an American former professional basketball player. He played three seasons as a shooting guard in the American Basketball Association (ABA), all as a member of the New York Nets (1970–73). He was drafted in the second round (29 overall) of the 1970 NBA draft from St. John's University by the Phoenix Suns, but he never played for them.