Joan B. Broderick Explained
| Joan Blanchette Broderick |
| Workplaces: | Montana State University |
| Alma Mater: | Northwestern University |
| Thesis Title: | Spectroscopic and mechanistic studies of chlorocatechol dioxygenase, a non-heme iron dioxygenase with broad substrate tolerance |
| Thesis Url: | https://www.worldcat.org/oclc/ |
| Thesis Year: | 1992 |
| Spouses: | )--> |
| Partners: | )--> |
Joan Blanchette Broderick is a professor of chemistry and biochemistry at Montana State University known for her work on bioinorganic chemistry, especially the chemistry of iron-sulfur interactions. She was elected a member of the National Academy of Sciences in 2022.[1]
Education and career
Broderick has an undergraduate degree from Washington State University, and an M.S. and a PhD from Northwestern University. Following her Ph.D., she was a postdoc at Massachusetts Institute of Technology and then an assistant professor at Amherst College. She held a faculty position at Michigan State University before moving to Montana in 2005.[2]
She has been recognized as a Saltman Lecturer and Women in Science Distinguished Professor at Montana State University.[3] In 2019, Broderick received the Alfred Bader Award in Bioinorganic or Bioorganic Chemistry from the American Chemical Society.[4]
Research
She has contributed to bioinorganic chemistry often with a focus on iron-sulfur proteins, including the radical SAM enzymes.[5] Her research also includes investigations into hydrogenase where she defines the assembly of the enzymes into functional units.[6] [7]
Selected publications
- Mulder . David W. . Boyd . Eric S. . Sarma . Ranjana . Lange . Rachel K. . Endrizzi . James A. . Broderick . Joan B. . Peters . John W. . Stepwise [FeFe]-hydrogenase H-cluster assembly revealed in the structure of HydAΔEFG . Nature . May 2010 . 465 . 7295 . 248–251 . 10.1038/nature08993. 20418861 . 2010Natur.465..248M . 1990191 .
- Peters . John W. . Schut . Gerrit J. . Boyd . Eric S. . Mulder . David W. . Shepard . Eric M. . Broderick . Joan B. . King . Paul W. . Adams . Michael W. W. . [FeFe]- and [NiFe]-hydrogenase diversity, mechanism, and maturation ]. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research . 1 June 2015 . 1853 . 6 . 1350–1369 . 10.1016/j.bbamcr.2014.11.021 . 25461840 . en . 0167-4889. free .
- Broderick . Joan B. . Duffus . Benjamin R. . Duschene . Kaitlin S. . Shepard . Eric M. . Radical S -Adenosylmethionine Enzymes . Chemical Reviews . 23 April 2014 . 114 . 8 . 4229–4317 . 10.1021/cr4004709 . 24476342 . 4002137 .
References
- Web site: 2022 NAS Election .
- Web site: 2017-10-09. People. 2021-10-07. Broderick Research Group. en.
- Web site: Joan Broderick - Chemistry and Biochemistry - Montana State University. www.chemistry.montana.edu.
- Web site: 2019 ACS National Award winners. Chemical & Engineering News. en. 2019-01-22.
- Broderick, J. B.; Duffus, B. R.; Duschene, K. S.; Shepard, E. M., "Radical S-Adenosylmethionine Enzymes", Chemical Reviews 2014, volume 114, 4229-4317. 10.1021/cr4004709
- Shepard. Eric M.. McGlynn. Shawn E.. Bueling. Alexandra L.. Grady-Smith. Celestine S.. George. Simon J.. Winslow. Mark A.. Cramer. Stephen P.. Peters. John W.. Broderick. Joan B.. 2010-06-08. Synthesis of the 2Fe subcluster of the [FeFe]-hydrogenase H cluster on the HydF scaffold. Proceedings of the National Academy of Sciences. en. 107. 23. 10448–10453. 10.1073/pnas.1001937107. 0027-8424. 2890834. 20498089. 2010PNAS..10710448S . free .
- Peters. John W.. Broderick. Joan B.. 2012-07-07. Emerging Paradigms for Complex Iron-Sulfur Cofactor Assembly and Insertion. Annual Review of Biochemistry. 81. 1. 429–450. 10.1146/annurev-biochem-052610-094911. 22482905 . 0066-4154.
