| João Manuel | |
| Fullname: | João Manuel Loureiro dos Santos |
| Birth Date: | 31 August 1967 |
| Birth Place: | Moimenta da Beira, Portugal |
| Death Place: | Guimarães, Portugal |
| Position: | Midfielder |
| Years1: | 1987–1988 |
| Clubs1: | Viseu e Benfica |
| Years2: | 1988–1992 |
| Clubs2: | Académico de Viseu |
| Caps2: | 51 |
| Goals2: | 7 |
| Years3: | 1992–1995 |
| Caps3: | 86 |
| Goals3: | 8 |
| Years4: | 1995–2004 |
| Clubs4: | União de Leiria |
| Caps4: | 251 |
| Goals4: | 11 |
| Years5: | 2004 |
| Clubs5: | Moreirense |
| Caps5: | 2 |
| Goals5: | 0 |
João Manuel Loureiro dos Santos, known as João Manuel (born 31 August 1967; died 18 May 2005 of multiple sclerosis) was a Portuguese football player.
He made his professional debut in the Primeira Liga for Académico de Viseu on 28 August 1988 as a starter in a 0–0 draw against Marítimo.[1] Over his career, he played 255 games on the top level of Portuguese football, most of them with União de Leiria, he also played in the UEFA Europa League and UEFA Intertoto Cup with the club.
He was called up to the Portugal national football team several times in 1996 and 1997, but stayed on the bench in each game he was on the roster.