| João Crisóstomo de Abreu e Sousa | |
| Order: | Prime Minister of Portugal |
| Term Start: | 11 October 1890 |
| Term End: | 18 January 1892 |
| Predecessor: | António de Serpa Pimentel |
| Successor: | José Dias Ferreira |
| Birth Date: | 27 January 1811 |
| Birth Place: | Lisbon, Kingdom of Portugal |
| Death Place: | Lisbon, Kingdom of Portugal |
| Party: | Independent |
João Crisóstomo de Abreu e Sousa (27 January 1811 in Lisbon – 7 January 1895 in Lisbon) was an army general who became the prime minister of Portugal between 14 October 1890 and 17 January 1892 in a non-partisan government organized by the Liga Liberal (Liberal League).