| Jim Holmes | |
| Position: | Pitcher |
| Bats: | Unknown |
| Throws: | Unknown |
| Birth Date: | 2 August 1882 |
| Birth Place: | Lawrenceburg, Kentucky |
| Death Place: | Jacksonville, Florida |
| Debutleague: | MLB |
| Debutdate: | September 8 |
| Debutyear: | 1906 |
| Debutteam: | Philadelphia Athletics |
| Finalleague: | MLB |
| Finaldate: | October 7 |
| Finalyear: | 1908 |
| Finalteam: | Brooklyn Superbas |
| Statleague: | MLB |
| Stat1label: | Win–loss record |
| Stat1value: | 1–5 |
| Stat2label: | Earned run average |
| Stat2value: | 3.49 |
| Stat3label: | Strikeouts |
| Stat3value: | 11 |
| Teams: |
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James Scott Holmes (August 2, 1882 in Lawrenceburg, Kentucky – March 10, 1960 in Jacksonville, Florida) was a pitcher in Major League Baseball. He pitched in 3 games for the Philadelphia Athletics during the 1906 season and in 13 games for the Brooklyn Superbas in 1908.