| Class: | Premier Handicap |
| Horse Race: | Jewson Handicap Chase |
| Location: | Cheltenham Racecourse, Cheltenham, Gloucestershire, England |
| Race Type: | Steeplechase |
| Sponsor: | Jewson |
| Website: | Cheltenham |
| Distance: | 3 miles 3 furlongs 71 yards (5,496 metres) |
| Surface: | Turf |
| Qualification: | Four-years-old and up |
| Weight: | Handicap Maximum: 11 st 12 lb |
| Purse: | £75,000 (2022) 1st: £42,713 |
|}The Jewson Handicap Chase is a Premier Handicap National Hunt race in Great Britain. It is a handicap steeplechase and is run at Cheltenham Racecourse in November, over a distance of about 3 miles and 3½ furlongs (3 miles 3 furlongs and 71 yards, or 5,496 metres).
From 1987 to 1998 the race was known as the Flowers Original Handicap Chase. The 1999 running was known as the Hoegaarden Handicap Chase. From 2000 to 2002 it was sponsored by Intervet and known as the Intervet Trophy. The 2003 race was run under the name of the Open Trophy. The race was sponsored by Servo from 2004 to 2009, Morson Group in 2010 and Rewards4Racing in 2011. In 2012 it was renamed the Henrietta Knight Handicap Chase in honour of Henrietta Knight, a recently retired trainer whose training successes included winning three Cheltenham Gold Cups with Best Mate. From 2013 to 2015 the race was sponsored by the Murphy Group.
Most successful horse:
Leading jockey (4 wins):
Leading trainer (4 wins):
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| Year | Winner | Age | Weight | Jockey | Trainer | |
|---|---|---|---|---|---|---|
| 1987 | Knock Hill | 11 | 10-00 | George Mernagh | John Webber | |
| 1988 | Run And Skip | 10 | 11-07 | Peter Scudamore | John Spearing | |
| 1989 | Royal Cedar | 8 | 10-01 | Richard Dunwoody | John McConnochie | |
| 1990 | Topsham Bay | 7 | 10-07 | Hywel Davies | David Barons | |
| 1991 | Ace of Spies | 10 | 09-09 | Adrian Maguire | Gill Jones | |
| 1992 | Belmount Captain | 7 | 10-03 | Richard Guest | Toby Balding | |
| 1993 | Royal Athlete | 10 | 12-00 | Graham Bradley | Jenny Pitman | |
| 1994 | Gold Cap | 9 | 10-00 | Richard Dunwoody | Philip Hobbs | |
| 1995 | Willsford | 12 | 12-00 | Warren Marston | Jenny Pitman | |
| 1996 | Evangelica | 6 | 10-00 | Tony McCoy | Martin Pipe | |
| 1997 | Banjo | 7 | 11-02 | Adrian Maguire | David Nicholson | |
| 1998 | Tennessee Twist | 8 | 10-00 | Norman Williamson | Jenny Pitman | |
| 1999 | Hanakham | 10 | 11-10 | Tony McCoy | Martin Pipe | |
| 2000 | Foxchapel King | 7 | 10-05 | Shay Barry | Mouse Morris | |
| 2001 | Hati Roy | 8 | 10-13 | Jim Culloty | Henrietta Knight | |
| 2002 | Stormez | 5 | 10-06 | Barry Geraghty | Martin Pipe | |
| 2003 | Shardam | 6 | 10-02 | Carl Llewellyn | Nigel Twiston-Davies | |
| 2004 | Stormez | 7 | 11-05 | Timmy Murphy | Martin Pipe | |
| 2005 | Innox | 9 | 10-06 | Tony McCoy | François Doumen | |
| 2006 | My Will | 6 | 11-06 | Ruby Walsh | Paul Nicholls | |
| 2007 | Sir Rembrandt | 11 | 10-02 | James White | Victor Dartnall | |
| 2008 | Joe Lively | 9 | 10-03 | Joe Tizzard | Colin Tizzard | |
| 2009 | Galant Nuit | 5 | 10-00 | Graham Lee | Ferdy Murphy | |
| 2010 | Midnight Chase | 8 | 11-09 | Dougie Costello | Neil Mulholland | |
| 2011 | Galaxy Rock | 7 | 10-10 | Tony McCoy | Jonjo O'Neill | |
| 2012 | Monbeg Dude | 7 | 10-00 | Jamie Moore | Michael Scudamore | |
| 2013 | Alvarado | 8 | 10-00 | Paul Moloney | Fergal O'Brien | |
| 2014 | Sam Winner | 7 | 11-12 | Sam Twiston-Davies | Paul Nicholls | |
| 2015 | Sausalito Sunrise | 7 | 11-03 | Richard Johnson | Philip Hobbs | |
| 2016 | Viconte Du Noyer | 7 | 10-13 | Harry Cobden | Colin Tizzard | |
| 2017 | Perfect Candidate | 10 | 10-12 | Paddy Brennan | Fergal O'Brien | |
| 2018 | Rock the Kasbah | 8 | 10-13 | Richard Johnson | Philip Hobbs | |
| 2019 | West Approach | 9 | 11-01 | Robbie Power | Colin Tizzard | |
| 2020 | Ramses De Teillee | 8 | 11-05 | Tom Scudamore | David Pipe | |
| 2021 | Yala Enki | 7 | 11-12 | Bryony Frost | Paul Nicholls | |
| 2022 | Does He Know | 7 | 12-00 | David Bass | Kim Bailey | |
| 2023 | Malina Girl | 6 | 11-07 | Sean Flanagan | Gavin Cromwell |