Jeremy Sanders Explained

Jeremy Sanders
Birth Name:Jeremy Keith Morris Sanders
Birth Date:3 May 1948[1]
Birth Place:London, England, UK
Nationality:English
Thesis Title:Paramagnetic shift reagents in N.M.R. spectroscopy
Thesis Url:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.471546
Thesis Year:1972
Doctoral Advisor:Dudley Williams[2]
Known For:Dynamic combinatorial chemistry
Fields:Supramolecular chemistry

Jeremy Keith Morris Sanders (born 3 May 1948[1]) is a British chemist and Emeritus Professor in the Department of Chemistry at the University of Cambridge. He is also Editor-in-Chief of Royal Society Open Science. He is known for his contributions to many fields including NMR spectroscopy and supramolecular chemistry. He served as the Pro-Vice-Chancellor for Institutional Affairs at the University of Cambridge, 2011–2015.[3] [4] [5] [6]

Education

Educated in London at Southmead Primary School and Wandsworth Comprehensive School, he then studied chemistry at Imperial College London where he graduated with a Bachelor of Science degree in 1969 and was awarded the Edmund White Prize. During 1969–72 he carried out his PhD research on lanthanide shift reagents, especially Eu(DPM), the original reagent developed before Eu(FOD) at Churchill College, Cambridge, supervised by Dudley Williams.[2]

Career and Research

Elected a fellow of Christ's College, Cambridge, in 1972, he spent a postdoctoral year in the Pharmacology Department, Stanford University before returning to Cambridge to become a Demonstrator in Chemistry. He was promoted to Lecturer (1978), Reader (1992) and then Professor (1996–2015). He was Head of the Chemistry Department 2000–2006, and Head of the School of Physical Sciences 2009–2011; he was also Deputy Vice-Chancellor 2006–2010 (responsible for overseeing the University's 800th Anniversary celebrations).

He was Chair from 2004 to 2008 of sub-panel 18 (Chemistry) for the UK 2008 Research Assessment Exercise.

NMR Spectroscopic achievements include the first complete analyses of the proton spectra of steroids through the pioneering use of NOEs and two-dimensional techniques,[7] and new understanding of the biophysical chemistry in vivo of microbial storage polymers.[8] [9]

In supramolecular chemistry, his porphyrin systems have led to one of the first experimental verifications of the predicted Marcus 'inverted region',[10] and the standard model (with Chris Hunter) of aromatic π-π interactions.[11] [12] He has used the coordination chemistry of Zn, Sn, Ru, Rh and Al oligoporphyrins to create new complex systems,[13] to develop new templated approaches in synthesis,[14] and to engineer the acceleration of intermolecular reactions within host cavities.[15]

Since the mid-1990s he has been in the forefront (with Jean-Marie Lehn and several other research groups) of developing Dynamic covalent chemistry and the closely related dynamic combinatorial chemistry.[16] In dynamic covalent chemistry, the most stable accessible product of a mixture is formed using thermodynamically controlled reversible reactions; in dynamic combinatorial chemistry a template is used to direct the synthesis of the molecule that best stabilises the template. In each case unpredictable molecules may be discovered that would not be designed or could not be prepared by conventional chemistry. These approaches have been particularly successful in preparing unpredictable Catenanes[17] [18] [19] and other complex macrocycles including a molecular knot.[20]

Sanders has also recently discovered helical supramolecular nanotubes capable of binding C60 Fullerene and other guests.[21]

Awards and honours

He was appointed Commander of the Order of the British Empire (CBE) in the 2014 Birthday Honours for services to scientific research.[24] Sanders' nomination for the Royal Society reads:

External links

Notes and References

  1. Web site: SANDERS, Prof. Jeremy Keith Morris . Who's Who 2016, A & C Black, an imprint of Bloomsbury Publishing plc, 2014; online edn, Oxford University Press .
  2. Web site: Dudley Williams obituary. . 24 November 2010.
  3. Web site: The Pro-Vice-Chancellors. University of Cambridge. 25 December 2011. dead. https://web.archive.org/web/20111213133916/http://www.admin.cam.ac.uk/offices/v-c/pvcs.html. 13 December 2011.
  4. Web site: Jeremy Sanders . Alanmacfarlane.com . 2009-09-22 . 2016-09-10 . dead . https://web.archive.org/web/20160303202145/http://www.alanmacfarlane.com/ancestors/sanders.htm . 3 March 2016 .
  5. 20508119. 2010. Stefankiewicz. A. R.. Chemistry. Harmony of the self-assembled spheres. Science. 328. 5982. 1115–6. Sanders. J. K.. 10.1126/science.1190821. 206527011.
  6. 12142534. 2002. Otto. S. Selection and amplification of hosts from dynamic combinatorial libraries of macrocyclic disulfides. Science. 297. 5581. 590–3. Furlan. R. L.. Sanders. J. K.. 10.1126/science.1072361. 2002Sci...297..590O. 42198823.
  7. J. Am. Chem. Soc., 1980, 102, 5703–5711
  8. 2492534. 1989. Barnard. G. N.. The poly-beta-hydroxybutyrate granule in vivo. A new insight based on NMR spectroscopy of whole cells. The Journal of Biological Chemistry. 264. 6. 3286–91. Sanders. J. K.. 10.1016/S0021-9258(18)94064-0. free.
  9. J. Am. Chem. Soc., 1994, 116, 2695–2702
  10. Chemical Physics, 1986, 104, 315–324
  11. 10.1021/ja00170a016. The nature of .pi.-.pi. Interactions. Journal of the American Chemical Society. 112. 14. 5525. 1990. Hunter . C. A. . Sanders . J. K. M. .
  12. 10.1021/ja021403x. 12515485. 124 Years of Publishing Original and Primary Chemical Research: 135,149 Publications, 573,453 Pages, and a Century of Excellence. Journal of the American Chemical Society. 125. 1. 1–8. 2003. Stang . P. J.. free.
  13. The Porphyrin Handbook; Ed. K. M. Kadish, K. M. Smith, R. Guilard, Academic Press, 2000, vol 3, 347; Inorg. Chem., 2001, 40, 2486; Inorg. Chem., 2008, 47, 87
  14. Accounts Chem. Res., 1993, 26, 469
  15. New J. Chem., 1998, 22, 493–502
  16. Angew. Chemie Intl. Edn., 2002, 41, 898; Chemical Reviews, 2006, 106, 3652; Accounts Chem. Res., 2012, 45, 2211–2221.
  17. 15761119. 2005. Lam. R. T.. Amplification of acetylcholine-binding catenanes from dynamic combinatorial libraries. Science. 308. 5722. 667–9. Belenguer. A. Roberts. S. L.. Naumann. C. Jarrosson. T. Otto. S. Sanders. J. K.. 10.1126/science.1109999. 2005Sci...308..667L. 30506228.
  18. J. Am. Chem. Soc., 2011, 133, 3198-3207;
  19. Angew. Chemie Intl. Edn., 2012, 51, 1443-1447.
  20. 23139329. 2012. Ponnuswamy. N. Discovery of an organic trefoil knot. Science. 338. 6108. 783–5. Cougnon. F. B.. Clough. J. M.. Pantoş. G. D.. Sanders. J. K.. 10.1126/science.1227032. 2012Sci...338..783P. 3250858.
  21. J. Am. Chem. Soc., 2012, 134, 566-573.
  22. Web site: Library and Archive Catalogue . The Royal Society . 5 March 2017 . https://web.archive.org/web/20170305061945/https://collections.royalsociety.org/DServe.exe?dsqIni=Dserve.ini&dsqApp=Archive&dsqDb=Catalog&dsqCmd=show.tcl&dsqSearch=(RefNo

    %27EC%2F1995%2F29%27)

    . London . dead . 25 April 2014 .
  23. Web site: Bürgenstock Conference . Stereochemistry-buergenstock.ch . 2016-09-10.
  24. Web site: Archived copy . 2014-06-14 . dead . https://web.archive.org/web/20140714160211/https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/319881/Birthday_Honours_2014_List.pdf . 14 July 2014 .

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