Jennifer S. Brodbelt Explained

Jennifer Sue Brodbelt
Field:Analytical Chemistry, Mass Spectrometry
Work Institutions:Purdue University, University of California, Santa Barbara, University of Texas at Austin
Alma Mater:Purdue University
Thesis Title:Aspects of ion chemistry in mass spectrometry
Thesis Url:https://purdue.primo.exlibrisgroup.com/permalink/01PURDUE_PUWL/ufs51j/alma99170054299801081
Thesis Year:1988
Doctoral Advisor:R. Graham Cooks
Known For:Mass Spectrometry
Prizes:Field and Franklin Award
Website:http://brodbelt.cm.utexas.edu/research/

Jennifer S. Brodbelt is an American chemist known for her research using mass spectrometry to characterize organic compounds, especially biopolymers and proteins.

Education and career

Brodbelt has an undergraduate degree from the University of Virginia and earned her Ph.D. from Purdue University where she worked on gas phase ion chemistry using mass spectrometry.[1] Following her Ph.D. she was a postdoc at the University of California, Santa Barbara[2] before joining the University of Texas at Austin in 1989.[3] As of 2016, she is the Roland Pettit Centennial Chair in the Department of Chemistry.[4] [5]

She was the president of the American Society for Mass Spectrometry for the period of 2014–2016.[6]

Research

Brodbelt's research centers on the development of mass spectrometry-based methods to characterize organic molecules.[7] [8] Brodbelt's early research established methods to use chemical ionization in ion trap mass spectrometers[9] [10] and applied this method to the analysis of petroleum samples.[11] She subsequently worked on gas-phase ion chemistry[12] and photodissociation[13] as methods to break apart organic compounds before they are analyzed by a mass spectrometer. Her work has led to the analysis of compounds including recreational drugs,[14] [15] sunscreen,[16] and pesticides.[17] Her work also includes investigations into proteins[18] and other organic compounds produced by bacteria including [19] [20]

Selected publications

Awards

She was awarded the Agnes Fay Morgan Research Award in 1995.[21] In 2019, Brodbelt received the Frank H. Field and Joe L. Franklin Award for Outstanding Achievement in Mass Spectrometry from the American Chemical Society.[22] In 2023, she was named one of the "Mentors and Educators" in the Power List by the Analytical Scientist.[23]

Notes and References

  1. Brodbelt-Lustig . Jennifer Sue . 1998 . Aspects of ion chemistry in mass spectrometry. Ph.D. . October 6, 2021.
  2. Brodbelt. Jennifer. Postdoctoral Research Fellowship in Chemistry. en.
  3. Web site: Jennifer S. Brodbelt - Professor of Biochemistry and Molecular Genetics in Austin, Texas, United States Of America eMedEvents. 2021-10-06. eMedEvents.com. en.
  4. Web site: Faculty. utexas.edu. December 13, 2016.
  5. Web site: Jennifer Brodbelt. utexas.edu. December 13, 2016.
  6. Web site: Past Presidents. 2019-04-19.
  7. Brodbelt. Jennifer S.. 1997. Analytical applications of ion-molecule reactions. Mass Spectrometry Reviews. en. 16. 2. 91–110. 10.1002/(SICI)1098-2787(1997)16:2<91::AID-MAS3>3.0.CO;2-4. 1997MSRv...16...91B . 1098-2787.
  8. Web site: 2019. Jennifer Brodbelt. 2021-10-06. The Analytical Scientist. en.
  9. Brodbelt. Jennifer S.. Louris. John N.. Cooks. R. Graham.. 1987-05-01. Chemical ionization in an ion trap mass spectrometer. Analytical Chemistry. 59. 9. 1278–1285. 10.1021/ac00136a007. 0003-2700.
  10. Brodbelt. Jennifer.. Liou. Chien Chung.. Donovan. Tracy.. 1991-07-01. Selective adduct formation by dimethyl ether chemical ionization in a quadrupole ion trap mass spectrometer and a conventional ion source. Analytical Chemistry. 63. 13. 1205–1209. 10.1021/ac00013a005. 0003-2700.
  11. Brodbelt. Jennifer S.. Cooks. R. Graham. Wood. Karl V.. Jackson. Thomas J.. 1986-01-01. The Analysis of Metalloporphyrins in Petroleum Using Tandem Mass Spectrometry. Fuel Science and Technology International. 4. 6. 683–698. 10.1080/08843758608915836. 1986FSTI....4..683B . 0884-3759.
  12. Brodbelt. J. S.. Liou. C.-C.. 1993-01-01. New frontiers in host-guest chemistry: The gas phase. Pure and Applied Chemistry. de. 65. 3. 409–414. 10.1351/pac199365030409. 31322707 . 1365-3075. free.
  13. Brodbelt. Jennifer S.. Wilson. Jeffrey J.. 2009. Infrared multiphoton dissociation in quadrupole ion traps. Mass Spectrometry Reviews. en. 28. 3. 390–424. 10.1002/mas.20216. 19294735 . 2009MSRv...28..390B . 1098-2787.
  14. Hall. Brad J. Brodbelt. Jennifer S. 1997-08-15. Determination of barbiturates by solid-phase microextraction (SPME) and ion trap gas chromatography–mass spectrometry. Journal of Chromatography A. en. 777. 2. 275–282. 10.1016/S0021-9673(97)00363-4. 9299725 . 0021-9673.
  15. Hall. Brad J.. Satterfield-Doerr. Mary. Parikh. Aashish R.. Brodbelt. Jennifer S.. 1998-05-01. Determination of Cannabinoids in Water and Human Saliva by Solid-Phase Microextraction and Quadrupole Ion Trap Gas Chromatography/Mass Spectrometry. Analytical Chemistry. 70. 9. 1788–1796. 10.1021/ac971228g. 9599579 . 0003-2700.
  16. Felix. Tonya. Hall. Brad J. S. Brodbelt. Jennifer. 1998-10-05. Determination of benzophenone-3 and metabolites in water and human urine by solid-phase microextraction and quadrupole ion trap GC–MS. Analytica Chimica Acta. en. 371. 2. 195–203. 10.1016/S0003-2670(98)00293-1. 1998AcAC..371..195F . 0003-2670.
  17. Reyzer. Michelle L. Brodbelt. Jennifer S. 2001-06-01. Analysis of fire ant pesticides in water by solid-phase microextraction and gas chromatography/mass spectrometry or high-performance liquid chromatography/mass spectrometry. Analytica Chimica Acta. en. 436. 1. 11–20. 10.1016/S0003-2670(01)00893-5. 2001AcAC..436...11R . 0003-2670.
  18. Shaw. Jared B.. Li. Wenzong. Holden. Dustin D.. Zhang. Yan. Griep-Raming. Jens. Fellers. Ryan T.. Early. Bryan P.. Thomas. Paul M.. Kelleher. Neil L.. Brodbelt. Jennifer S.. 2013-08-28. Complete Protein Characterization Using Top-Down Mass Spectrometry and Ultraviolet Photodissociation. Journal of the American Chemical Society. 135. 34. 12646–12651. 10.1021/ja4029654. 0002-7863. 3757099. 23697802.
  19. Hankins. Jessica V.. Madsen. James A.. Giles. David K.. Brodbelt. Jennifer S.. Trent. M. Stephen. 2012-05-29. Amino acid addition to Vibrio cholerae LPS establishes a link between surface remodeling in Gram-positive and Gram-negative bacteria. Proceedings of the National Academy of Sciences. en. 109. 22. 8722–8727. 10.1073/pnas.1201313109. 0027-8424. 3365186. 22589301. 2012PNAS..109.8722H . free .
  20. Han. Sang-Wook. Lee. Sang-Won. Bahar. Ofir. Schwessinger. Benjamin. Robinson. Michelle R.. Shaw. Jared B.. Madsen. James A.. Brodbelt. Jennifer S.. Ronald. Pamela C.. 2012. Tyrosine sulfation in a Gram-negative bacterium. Nature Communications. en. 3. 1. 1153. 10.1038/ncomms2157. 2041-1723. 4305400. 23093190. 2012NatCo...3.1153H .
  21. Web site: 2021-10-06. Past Award Winners Iota Sigma Pi. 2021-10-06. https://web.archive.org/web/20211006120359/https://www.iotasigmapi.org/past-award-winners . 2021-10-06 .
  22. 2017-01-02. Frank H. Field & Joe L. Franklin Award for Outstanding Achievement in Mass Spectrometry: Vicki H. Wysocki. C&EN Global Enterprise. 95. 1. 49–50. 10.1021/cen-09501-awards054. 2474-7408. free.
  23. Web site: 2023-09-10 . The Power List 2023 . 2023-09-02 . The Analytical Scientist . en.

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