Jedi2 Explained

Jedi2 is a chemical compound which acts as an agonist for the mechanosensitive ion channel PIEZO1, and is used in research into the function of touch perception.^{[1] [2]}

See also

• Yoda1 and Jedi1

Notes and References

1. Wang Y, Chi S, Guo H, Li G, Wang L, Zhao Q, Rao Y, Zu L, He W, Xiao B . 6 . A lever-like transduction pathway for long-distance chemical- and mechano-gating of the mechanosensitive Piezo1 channel . Nature Communications . 9 . 1 . 1300 . April 2018 . 29610524 . 10.1038/s41467-018-03570-9 . 5880808 . 2018NatCo...9.1300W . free .
2. Fang XZ, Zhou T, Xu JQ, Wang YX, Sun MM, He YJ, Pan SW, Xiong W, Peng ZK, Gao XH, Shang Y . Structure, kinetic properties and biological function of mechanosensitive Piezo channels . Cell & Bioscience . 11 . 1 . 13 . January 2021 . 33422128 . 7796548 . 10.1186/s13578-020-00522-z . free .