| Office: | President of the Regional council of Grand Est |
| Term Start: | 20 October 2017 |
| Term End: | 30 December 2022 |
| Predecessor: | Philippe Richert |
| Successor: | Franck Leroy |
| Office2: | Mayor of Mulhouse |
| Term Start2: | 2010 |
| Term End2: | 2017 |
| Predecessor2: | Jean-Marie Bockel |
| Successor2: | Michèle Lutz |
| Birth Place: | Mulhouse, France |
| Nationality: | French |
| Alma Mater: | University of Strasbourg |
Jean Rottner (pronounced as /fr/; born 28 January 1967) is a French politician of the political party The Republicans who was mayor of Mulhouse from 2010 to 2017, and was President of the regional council of Grand Est from 2017 to 2022.
Born as a son of teachers, Jean Rottner studied medicine at the University of Strasbourg.