| Jean-François Humbert | |
| Office: | Senator for the Doubs |
| Alongside: | Claude Jeannerot & Martial Bourquin |
| Term Start: | 27 September 1998 |
| Predecessor: | Jean Pourchet |
| Office2: | Regional Councillor from Doubs |
| Term Start2: | 1986 |
| Office3: | 5th President of Franche-Comté |
| Term Start3: | 1998 |
| Term End3: | 2004 |
| Predecessor3: | Pierre Chantelat |
| Successor3: | Raymond Forni |
| Office4: | Leader of the Opposition |
| Term Start4: | 2004 |
| Term End4: | 2009 |
| Successor4: | Sylvie Vermeillet |
| Birth Date: | 17 October 1952 |
| Nationality: | French  |
Jean-François Humbert (in French pronounced as /ʒɑ̃ fʁɑ̃swa œ̃bɛʁ/; born 17 October 1952) is a French politician and a member of the Senate of France. He represents the Doubs department and is a member of the Union for a Popular Movement Party.
In the 2004 Franche-Comté regional election, he solicited reelection as President of Franche-Comté but was defeated by Socialist Raymond Forni.
On 21 September 2008 he was narrowly reelected as Senator.[1]
On 17 October 2009 he announced that he would challenge Socialist President Marie-Marguerite Dufay and UMP candidate Alain Joyandet in the 2010 Franche-Comté regional election.[2] Nine days later, he resigned the Presidency of UMP Group in the Regional Council.[3]