| Jaqué River | |
| Map: | File:Jaque_River.svg |
| Map Size: | 400px |
| Pushpin Map: | Panama |
| Source1 Location: | Darién National Park |
| Mouth Location: | Jaqué, Darién Province |
| Mouth Coordinates: | 7.5°N -78.05°W |
| Subdivision Type1: | Country |
| Subdivision Name1: | Panama |
The Jaqué River is a river in the Darién Province of southern Panama. It flows generally westward from its source in the Darién National Park to the town of Jaqué, where it enters the Pacific Ocean.