| Country: | JPN |
| Type: | National |
| Route: | 449 |
| Map Custom: | yes |
| Length Km: | 20.3 |
| Length Ref: | [1] |
| Direction A: | West |
| Terminus A: | in Motobu, Okinawa |
| Direction B: | East |
| Terminus B: | in Nago, Okinawa |
| Previous Type: | Route |
| Previous Route: | 448 |
| Next Type: | Route |
| Next Route: | 450 |
National Route 449 is a national highway of Japan connecting Motobu, Okinawa and Nago, Okinawa in Japan, with a total length of 20.3 km (12.61 mi).