| Country: | JPN |
| Type: | National |
| Route: | 153 |
| Map Custom: | yes |
| Length Km: | 213.4 |
| Length Ref: | [1] |
| Established: | 1953 |
| Direction A: | North |
| Terminus A: | in Shiojiri, Nagano |
| Direction B: | South |
| Terminus B: | in Higashi-ku, Nagoya |
| Previous Type: | Route |
| Previous Route: | 152 |
| Next Type: | Route |
| Next Route: | 154 |
National Route 153 is a national highway of Japan connecting Higashi-ku, Nagoya and Shiojiri, Nagano in Japan, with a total length of 213.4 km (132.6 mi).