| Country: | JPN |
| Type: | National |
| Route: | 108 |
| Map Custom: | yes |
| Map Notes: | Japan National Route 108 highlighted in red |
| Length Km: | 186.9 |
| Length Ref: | [1] |
| Established: | 1953 |
| Direction A: | South |
| Terminus A: | in Ishinomaki, Miyagi |
| Junction: | |
| Direction B: | North |
| Terminus B: | in Yurihonjō, Akita |
| Previous Type: | Route |
| Previous Route: | 107 |
| Next Type: | Route |
| Next Route: | 112 |
National Route 108 is a national highway of Japan connecting Ishinomaki and Yurihonjō, Akita in Japan, with a total length of 186.9km (116.1miles).
Route 108 was originally designated on 18 May 1953 as a route from Ishinomaki to Shinbori (now Sakata) via Furukawa (now Osaki). On 1 April 1963, the route was shortened to Furukawa and rerouted to Yokote, replacing Route 109; the original route to Sakata was incorporated into Route 47. On 1 April 1970, the northern terminus was moved to Honjo (now Yurihonjō).