Janikhel (Pushto; Pashto: جانيخېل ولسوالۍ, Persian: ولسوالی جانیخیل) is a district in Paktika Province, in eastern Afghanistan. It was created in 2004 out of a part of Khairkot District.
Like in the rest of Afghanistan, no exact population numbers are available. The Afghan Ministry of Rural Rehabilitation & Development (MRRD) along with UNHCR and Central Statistics Office (CSO) of Afghanistan estimated the population of the district to be around 36,237 (CSO 2019).[1] According to the same sources, Pashtuns make up 100% of the total population.