| Janes Creek | |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | Missouri |
| Subdivision Type3: | Region |
| Subdivision Name3: | Washington and Iron counties |
| Source1 Location: | Iron County, Missouri |
| Source1 Coordinates: | 37.7067°N -90.8533°W |
| Mouth Location: | Washington County |
| Mouth Coordinates: | 37.7686°N -90.8644°W |
| Mouth Elevation: | 272m (892feet) |
Janes Creek is a stream in Iron and Washington counties of the U.S. state of Missouri. It is a tributary of Big River. The headwaters of the stream arise in northern Iron County just north of Missouri Route 32 west of Banner. The confluence with Big River is in southern Washington County between Peoria and Belgrade adjacent to Missouri Route JJ.[1]
The namesake of Janes Creek is unknown.[2]