Jane Stewart (scientist) explained

Jane Stewart
Fields:	Behavioral neuroscience
Workplaces:	Concordia University
Alma Mater:	Queen's University, University of London

Jane Stewart is a Canadian neuroscientist who has been active in the fields of psychology, psychiatry, and psychopharmacology. She is a professor emerita at Concordia University in Montreal, Canada.

Career

Stewart earned a Bachelor of Arts degree in psychology and biology from Queen's University in 1956, and PhD in psychology in 1959 from the University of London, England.^{[1] [2]} She then started working for Ayerst Pharmaceuticals in Montreal and subsequently joined Concordia University in 1962,^[3] where she served as chair of the Department of Psychology (1969–1974) and director of the Center for Studies in Behavioral Neurobiology (1990–1997).^[1] She served on many grant review committees and on the editorial boards of 11 peer-reviewed scientific journals.^[1]

Research

Stewart has made seminal contributions to different areas of research, such as conditioned drug effects,^{[4] [5]} the motivational effects of drugs,^[6] circadian rhythms,^[7] antidepressant and antipsychotic drug action,^{[8] [9]} and sexual behavior.^{[10] [11]}

Honors

Stewart was awarded an honorary degree from Queen's University and is a Fellow of the American Association for the Advancement of Science, the American Psychological Association, the Canadian Psychological Association, and the Royal Society of Canada.^[1] She also received the highest civilian honor in her country, being appointed Officer in the Order of Canada in 2007.^[1] A special issue of the journal Biological Psychiatry was dedicated to her on the occasion of her retirement in 2008.^[1]

Significant papers

• Kalivas PW, Stewart J . Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity . . 16 . 3 . 223–44 . 1991 . 1665095 . 10.1016/0165-0173(91)90007-U. 10775295 . (cited over 1300 times)^[12]
• Stewart J, de Wit H, Eikelboom R . Role of unconditioned and conditioned drug effects in the self-administration of opiates and stimulants . . 91 . 2 . 251–68 . April 1984 . 6571424 . 10.1037/0033-295X.91.2.251. (cited over 600 times)^[12]
• de Wit H, Stewart J . Reinstatement of cocaine-reinforced responding in the rat . . 75 . 2 . 134–43 . 1981 . 6798603 . 10.1007/BF00432175. 2627859 . (cited over 400 times)^[12]
• Stewart J, Badiani A . Tolerance and sensitization to the behavioral effects of drugs . . 4 . 4 . 289–312 . 1993 . 11224198 . 10.1097/00008877-199308000-00003. (cited over 350 times)^[12]
• Shaham Y, Shalev U, Lu L, De Wit H, Stewart J . The reinstatement model of drug relapse: history, methodology and major findings . Psychopharmacology . 168 . 1–2 . 3–20 . July 2003 . 12402102 . 10.1007/s00213-002-1224-x . 144348217 . (cited over 300 times)^[12]

Notes and References

1. de Wit H, Shaham Y . Incentive motivation, conditioning, stress, and neuropsychiatric disorders: A tribute to Jane Stewart . Biological Psychiatry . 65 . 10 . 827–8 . May 2009 . 19398047 . 10.1016/j.biopsych.2008.12.012 . 2716031.
2. Web site: Jane Stewart CV. 2015. Concordia University. 2019-12-13.
3. Web site: Jane Stewart. www.concordia.ca. 2016-03-09.
4. Eikelboom R, Stewart J . Conditioning of drug-induced physiological responses . . 89 . 5 . 507–28 . September 1982 . 7178331 . 10.1037/0033-295X.89.5.507.
5. Stewart J . Neurobiology of conditioning to drugs of abuse . . 654 . 335–46 . June 1992 . 1 . 1321575 . 10.1111/j.1749-6632.1992.tb25979.x. 1992NYASA.654..335S . 29924902 .
6. Stewart J, de Wit H, Eikelboom R . Role of unconditioned and conditioned drug effects in the self-administration of opiates and stimulants . Psychological Review . 91 . 2 . 251–68 . April 1984 . 6571424 . 10.1037/0033-295X.91.2.251.
7. Amir S, Stewart J . Resetting of the circadian clock by a conditioned stimulus . . 379 . 6565 . 542–5 . February 1996 . 8596633 . 10.1038/379542a0. 1996Natur.379..542A . 4325922 .
8. Stewart J, Rajabi H . Initial increases in extracellular dopamine in the ventral tegmental area provide a mechanism for the development of desipramine-induced sensitization within the midbrain dopamine system . . 23 . 4 . 258–64 . August 1996 . 8855510 . 10.1002/(SICI)1098-2396(199608)23:4<258::AID-SYN3>3.0.CO;2-6. 37789995 .
9. Samaha AN, Seeman P, Stewart J, Rajabi H, Kapur S . "Breakthrough" dopamine supersensitivity during ongoing antipsychotic treatment leads to treatment failure over time . . 27 . 11 . 2979–86 . March 2007 . 17360921 . 6672560 . 10.1523/JNEUROSCI.5416-06.2007 .
10. Mitchell JB, Stewart J . Facilitation of sexual behaviors in the male rat associated with intra-VTA injections of opiates . . 35 . 3 . 643–50 . March 1990 . 1971113 . 10.1016/0091-3057(90)90302-X. 45442957 .
11. Mitchell JB, Stewart J . Facilitation of sexual behaviors in the male rat in the presence of stimuli previously paired with systemic injections of morphine . Pharmacology Biochemistry and Behavior . 35 . 2 . 367–72 . February 1990 . 2320644 . 10.1016/0091-3057(90)90171-D. 6336713 .
12. [Web of Science]