Jan Holmgren Explained

Jan Roland Holmgren (born in Borås, Sweden) is a Swedish physician, microbiologist, immunologist, and vaccinologist, known for his research on cholera and mucosal immunology, specifically, for his leadership in developing "the world's first effective oral cholera vaccine".[1]

Biography

At the University of Gothenburg (Göteborgs universitet in Swedish), Holmgren graduated in 1965 with a bachelor of medicine degree, in 1969 with a Ph.D., and in 1973 with an M.D. His 1969 doctoral dissertation dealt with immunological aspects of urinary tract infections in children.[2] At the University of Gothenburg, he was appointed in 1969 a docentry and in 1970 an associate professorship. From 1971 to 1980 he held research positions at the Swedish Medical Research Council. In 1980 he was appointed to the University of Gothenburg's professorial chair in medical microbiology and immunology as successor to Örjan Ouchterlony upon the latter's retirement.[3] In addition to his professorship, Holmgren was appointed founding director of the Göteborg University Vaccine Research Institute (GUVAX), which was created in 2002.[4] He is the author or co-author of more than 600 scientific papers.[5]

His research contributed to the development of a vaccine together with Ann-Mari Svennerholm against Enterotoxigenic Escherichia coli (ETEC). Furthermore, his research has applications to understanding immunological mechanisms, such as immunological tolerance by oral immunization, and also to developing vaccines against some autoimmune diseases and allergies.

He received in 1977 the Swedish Academy of Sciences Prize for Medicine (Hilda and Alfred Erikssons Prize) and in 1994 both the Louis-Jeantet Prize for Medicine[6] and the Söderbergska Prize of the Swedish Medical Society.[7] He received in 2017 the Albert B. Sabin Gold Medal[1] [8] and in 2018 the Prince Mahidol Award in Public Health.[9] He is a member of the Royal Swedish Academy of Science[10] and the Swedish Academy of Engineering. He was a board member of the Knut and Alice Wallenberg Foundation from 1995 to 2017 and has served on the boards of other national and international organizations for research on vaccines, infections, and global health; the other organizations include the Global Alliance for Vaccines and Immunization (GAVI) and the International Vaccine Institute (IVI).[4]

He married Ann-Mari Svennerholm, who was his first Ph.D. student. They have worked together since 1970.[11] They have a son and two daughters.

Selected publications

  1. Web site: Dr. Jan Holmgren Receives 2017 Albert B. Sabin Gold Medal Award. April 25, 2017. Sabin Vaccine Institute.
  2. Book: Holmgren, Jan . On the antibody response to E. coli antigens in immunized rabbits and in children with pyelonephritis . 1969 . University of Gothenburg.
  3. Cover Legend. Cancer Research. 46. 5. May 1986.
  4. Web site: Professor Jan Holmgren, MD. pneumoADIP.
  5. Web site: Luminary in Vaccine Research. 2017. European Biotechnology.
  6. Web site: Professor Jan Holmgren, Winner of the 1994 Louis-Jeantet Prize for medicine. Fondation Louis-Jeantet. (in French)
  7. Web site: Söderbergska Priset. Torsten Söderbergs Stiftelse.
  8. Web site: Q&A with Jan Holmgren. April 25, 2017. Sabin Vaccine Institute.
  9. Web site: Otmani, Malin. Jan Holmgren receives global health award. Nordic Life Science News. November 23, 2018.
  10. Web site: Jan Holmgren. Kungl Vetenskaps Akademien.
  11. Web site: Their research produced global benefits. Tidningen Curie. 28 May 2019.

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