Jan Löwe Explained

Professor Jan Löwe
Birth Date:14 July 1967
Nationality:German
Term Start1:2018
Predecessor1:Sir Hugh Pelham
Module:
Embed:yes
Thesis Title:Crystal structure of the 20S proteasome from T. acidophilum
Thesis Url:http://www.worldcat.org/oclc/117901549
Thesis Year:1995
Doctoral Advisor:Robert Huber
Awards:EMBO Member (2004)
EMBO Gold Medal (2007)
Known For:Structural biology of bacterial cytoskeletons

Jan Löwe (born 14 July 1967) is a German molecular and structural biologist and the Director of the Medical Research Council (MRC) Laboratory of Molecular Biology (LMB) in Cambridge, UK. He became Director of the MRC-LMB in April 2018,[1] succeeding Sir Hugh Pelham. Löwe is known for his contributions to the current understanding of bacterial cytoskeletons.[2]

Education

Löwe was awarded a Diploma in Chemistry by the University of Hamburg in 1992. He was then awarded his Dr. rer. nat. in 1995 by the Technische Universität München, for his thesis work on the structure of the proteasome[3] completed at the Max Planck Institute of Biochemistry under the supervision of Robert Huber.

Career and research

Löwe worked briefly as a postdoctoral researcher at the Max Planck Institute of Biochemistry,[4] before moving to MRC-LMB in 1996 to take up an EMBO long-term fellowship to work on crystallising FtsZ, a bacterial homologue of eukaryotic tubulin, with Linda A. Amos.[5] Löwe became a group leader at MRC-LMB in 1998 and was awarded tenure in 2002. His group has largely worked on the structural and molecular biology of prokaryotic cytoskeletons, but has also made important contributions to the current understanding of cell division and DNA partitioning in both prokaryotes and eukaryotes. Löwe became the Director of MRC-LMB in April 2018, having formerly been Deputy Director (2016-18) and Joint Head of the Structural Studies Division at the institute (2010-18).In 2018, the title of Honorary Professor of Structural and Molecular Microbiology at the University of Cambridge wasconferred on him.[6]

Awards and honours

Notes and References

  1. News: Brackley. Paul. Dr Jan Löwe says he's 'humbled' to take over as director of MRC Laboratory of Molecular Biology. 27 April 2018. Cambridge Independent. Online. 14 February 2018.
  2. Web site: Dr Jan Löwe FRS. royalsociety.org. 30 April 2018. en-gb. Anon. Royal Society. London. 2008. One or more of the preceding sentences incorporates text from the royalsociety.org website where:
  3. Lowe. J. Stock. D. Jap. B. Zwickl. P. Baumeister. W. Huber. R. Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution. Science. 1995. 268. 5210. 533–539. 10.1126/science.7725097. 7725097. 1995Sci...268..533L.
  4. Web site: Jan Löwe CV. www.leopoldina.org. 30 April 2018.
  5. Löwe. Jan. Amos. Linda A.. Crystal structure of the bacterial cell-division protein FtsZ. Nature. 1998. 391. 6663. 203–206. 10.1038/34472. 9428770. 1998Natur.391..203L. 4330857.
  6. http://www.admin.cam.ac.uk/reporter/2018-19/weekly/6519/section3.shtml Cambridge University Reporter CXLIX No 6519, 26 September 2018
  7. Web site: EMBO profile. people.embo.org. 30 April 2018.
  8. Web site: Gold medal announcement. EMBO. 30 April 2018.
  9. Web site: List of Members. www.leopoldina.org. 30 April 2018. en.