| Type: | Bishop |
| James Keefe | |
| Bishop of Kildare and Leighlin | |
| Province: | Dublin |
| Diocese: | Kildare and Leighlin |
| See: | Kildare |
| Appointed: | 1752 |
| Term End: | 1788 |
| Predecessor: | Bishop James Gallagher |
| Successor: | Bishop Daniel Delany |
| Ordained By: | Bishop James Bernard Dunne |
| Nationality: | Irish |
| Religion: | Roman Catholic |
James Keefe was an Irish RomanCatholic cleric who was the founder of St. Patrick's, Carlow College. He was Bishop of Kildare and Leighlin for over 35 years (1752-1787).[1] He lived most of his time at Tullow, County Carlow.
He was preceded by Bishop James Gallagher in 1737 and succeeded by Bishop Daniel Delany in 1787, who was his co-adjutor Bishop and also helped in the foundation of Carlow College.