| James Jefferson | |
| Position: | Defensive back |
| Number: | 26, 20 |
| Birth Date: | 18 November 1963 |
| Birth Place: | Portsmouth, Virginia, U.S. |
| Height Ft: | 6 |
| Height In: | 1 |
| Weight Lbs: | 199 |
| High School: | Kingsville (TX) Henrietta M. King |
| College: | Texas A&M-Kingsville |
| Pastteams: | |
| Highlights: | |
| Statlabel1: | Interceptions |
| Statvalue1: | 2 |
| Statlabel2: | Sacks |
| Statvalue2: | 1.0 |
| Cflstatlabel1: | Interceptions |
| Cflstatvalue1: | 17 |
| Cflstatlabel2: | Touchdowns |
| Cflstatvalue2: | 2 |
James Andrew Jefferson III (born November 18, 1963) is a former American and Canadian football defensive back in the National Football League (NFL) and Canadian Football League (CFL). He played for the Seattle Seahawks of the NFL and the Winnipeg Blue Bombers and BC Lions of the CFL, and also won two Grey Cup championships, one with the Blue Bombers in 1988 and another with the Lions in 1994. Jefferson played college football at Texas A&M-Kingsville.[1]