| James E. Cunningham | |
| Birth Date: | 28 August 1916 |
| Birth Place: | Santa Barbara, California, U.S. |
| State Senate: | California |
| District: | 36th |
| Term: | January 8, 1951 – September 10, 1957 |
| Preceded: | Ralph E. Swing |
| Succeeded: | Raymond H. Gregory |
| Party: | Republican |
| Spouse: | Louise Ruth Cunningham |
| Children: | 6 |
| Allegiance: |  United States |
| Branch: | |
| Battles: | World War II |
| Office2: | Mayor of San Bernardino |
| Order2: | 19th |
| Predecessor2: | Will C. Seccombe |
| Successor2: | Clarence T. Johnson |
| Termstart2: | May 12, 1947 |
| Termend2: | December 15, 1950 |
James E. Cunningham (August 28, 1916 – June 6, 1992) was an American politician who served in the California State Senate for the 36th district from 1951 to 1957 and during World War II he served in the United States Army.[1] He was mayor of San Bernardino and worked as a judge.[2]