| James Dana | |
| Office: | 5th Mayor of Charlestown, Massachusetts |
| Term Start: | 1858 |
| Term End: | 1860 |
| Office2: | Clerk of Courts of Middlesex County, Massachusetts |
| Term Start2: | September 1, 1859 |
| Term End2: | December 1, 1859 |
| Predecessor2: | John Quincy Adams Griffin |
| Successor2: | Benjamin Franklin Ham |
| Birth Date: | November 8, 1811 |
| Birth Place: | Charlestown, Massachusetts |
| Death Date: | June 4, 1890 |
| Death Place: | Dorchester, Massachusetts |
| Occupation: | Lawyer |
| Alma Mater: | Harvard |
| Signature: | James Dana (Massachusetts) signature.png |
James Dana (November 8, 1811 – June 4, 1890) was a Massachusetts politician who was the fifth mayor of Charlestown, Massachusetts, USA.
Dana was born in Charlestown to Samuel and Rebecca (née Barrett) Dana.
Dana was educated at Lawrence Academy, in Groton, Massachusetts, and graduated from Harvard College in the class of 1830.