| Honorific Prefix: | Nawab Sardar His Excellency |
| Jam Sadiq Ali | |
| Order: | 20th Chief Minister of Sindh |
| Order2: | Nawab of Sanghar |
| Predecessor2: | Nawab Jam Kambho Khan |
| Successor2: | Nawab Jam Mashooq Ali Nawab Jam Zulfiqar Ali Khan |
| Term Start: | 6 August 1990 |
| Term End: | 5 March 1992 |
| Predecessor: | Aftab Shahban Mirani |
| Successor: | Syed Muzaffar Hussain Shah |
| Birth Place: | Jam Nawaz Ali, Sanghar District, Sindh |
| Residence: | Jam Nawaz Ali, Sanghar District, Sindh |
| Death Place: | Karachi |
| Profession: | Nawab of Sanghar, Politician |
| Party: | Independent |
Nawab Jam Sadiq Ali (Urdu: جام صادق علی ) (ca. 1934 - 5 March 1992) was a politician from Sindh, Pakistan. He was the Nawab of Sanghar and Sardar of Junejo tribe and belonged to the ruling dynasty of Samaa Ja'ams who ruled Sindh over two centuries up to middle of 1700. He died in March 1992, and was succeeded by his son Nawab Jam Mashooq Ali Khan. Nawab Jam Mashooq Ali Khan, who had served as a federal minister and a member of the National Assembly of Pakistan multiple times, died in 2018 snd was succeeded by Nawab Jam Zulfiquar Ali Khan, who is the current Chief of the Samaa Dynasty, Chief of Juneja tribe and Nawab of Sanghar.
Jam Sadiq Ali Khan was Chief Minister of Sindh from 6 August 1990 to 5 March 1992. He was the Sardar of the Samma Jam and Junejo tribes and the Nawab of Sanghar. During Benazir Bhutto's 20-month Government, Nawab Jam Sadiq Ali served as an adviser but eventually resigned because of differences and was an archenemy of former Prime Minister Benazir Bhutto. After Benazir Bhutto was forced to step down in August 1990 because of corruption charges, he was elected Chief Minister of Sindh.
Jam Sadiq Ali Khan died on 5 March 1992 of cirrhosis of the liver at his home in Karachi. The Sindh government declared three days of mourning, closing government offices and schools. He was buried at his ancestral graveyard in city Jam Nawaz Ali.