| Jacuípe River | |
| Source1 Location: | Alagoas state |
| Mouth: | Una River |
| Subdivision Type1: | Country |
| Subdivision Name1: | Brazil |
The Jacuípe River is a river along the border between Alagoas and Pernambuco states in eastern Brazil. It flows into the Una River on the border of Barreiros and Água Preta municipalities in the latter state.