Jacqueline Afine Toxopeus (born 11 December 1964 in Wageningen, Gelderland) is a former Dutch field hockey international playing in goal. She is undoubtedly one of the finest goalkeepers in Dutch women's field hockey since Det de Beus. Toxopeus, nicknamed Tox, played for several clubs in the Netherlands, but ended her career with HC Den Bosch. In the spring of 2006 she made a short comeback with HC Rotterdam after several injuries in the squad.