| Official Name: | Jacksonboro, South Carolina |
| Pushpin Map: | South Carolina#USA |
| Pushpin Label: | Jacksonboro |
| Pushpin Label Position: | top |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type1: | State |
| Subdivision Name1: | South Carolina |
| Subdivision Type2: | County |
| Subdivision Name2: | Colleton |
| Unit Pref: | Imperial |
| Area Footnotes: | [1] |
| Area Total Km2: | 37.47 |
| Area Land Km2: | 37.47 |
| Area Water Km2: | 0.00 |
| Area Total Sq Mi: | 14.47 |
| Area Land Sq Mi: | 14.47 |
| Area Water Sq Mi: | 0.00 |
| Population As Of: | 2020 |
| Population Footnotes: | [2] |
| Population Total: | 412 |
| Population Density Km2: | 10.99 |
| Population Density Sq Mi: | 28.47 |
| Timezone: | Eastern (EST) |
| Utc Offset: | -5 |
| Timezone Dst: | EDT |
| Utc Offset Dst: | -4 |
| Elevation Ft: | 23 |
| Coordinates: | 32.7703°N -80.4544°W |
| Postal Code Type: | ZIP code |
| Postal Code: | 29446 |
| Area Code: | 843 and 854 |
| Blank Name: | GNIS feature ID |
| Blank Info: | 1246146 |
Jacksonboro is an unincorporated community and census-designated place located in southeastern Colleton County, South Carolina, United States, along the west side of the Edisto River. Jacksonboro serves as a primary junction along U.S. Highway 17 between Charleston to the east and Beaufort to the southwest. Walterboro, the Colleton County seat, is to the northwest via South Carolina Highway 64. The population of Jacksonboro was 478 as of the 2010 census.[3]
Jacksonboro was founded in the 1730s, and named after John Jackson, the original owner of the town site.[4] The Pon Pon Chapel was listed in the National Register of Historic Places in 1972.