JWH-184 explained

JWH-184 is a synthetic cannabinoid receptor ligand from the naphthylmethylindole family. It is the carbonyl-reduced derivative of related compound JWH-122. The binding affinity of JWH-184 for the CB₁ receptor is reported as K_i = 23 ± 6 nM.^[1]

In the United States, all CB₁ receptor agonists of the 3-(1-naphthylmethane)indole class such as JWH-184 are Schedule I Controlled Substances.

See also

• JWH-018
• JWH-122
• JWH-185

Notes and References

1. Huffman JW, Mabon R, Wu MJ, Lu J, Hart R, Hurst DP, Reggio PH, Wiley JL, Martin BR . 6 . 3-Indolyl-1-naphthylmethanes: new cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB(1) cannabinoid receptor . Bioorganic & Medicinal Chemistry . 11 . 4 . 539–49 . February 2003 . 12538019 . 10.1016/s0968-0896(02)00451-0 . 29107765 .