JWH-030 explained

JWH-030 is a research chemical which is a cannabinoid receptor agonist.[1] It has analgesic effects and is used in scientific research.[2] It is a partial agonist at CB1 receptors, with a Ki of 87 nM, making it roughly half the potency of THC.[3] It was discovered and named after John W. Huffman.

In the United States, CB1 receptor agonists of the 3-(1-naphthoyl)pyrrole class such as JWH-030 are Schedule I Controlled Substances.

See also

Notes and References

  1. Lainton JA, Huffman JW, Martin BR, Compton DR . 1-Alkyl-3-(1-naphthoyl) pyrroles: A new class of cannabinoid. . Tetrahedron Letters . February 1995 . 36 . 9 . 1401–4 . 10.1016/0040-4039(95)00016-6 .
  2. Pertwee RG, Griffin G, Lainton JA, Huffman JW . Pharmacological characterization of three novel cannabinoid receptor agonists in the mouse isolated vas deferens . European Journal of Pharmacology . 284 . 3 . 241–7 . September 1995 . 8666005 . 10.1016/0014-2999(95)00318-f .
  3. Griffin G, Atkinson PJ, Showalter VM, Martin BR, Abood ME . Evaluation of cannabinoid receptor agonists and antagonists using the guanosine-5'-O-(3-[35S]thio)-triphosphate binding assay in rat cerebellar membranes . The Journal of Pharmacology and Experimental Therapeutics . 285 . 2 . 553–60 . May 1998 . 9580597 .

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "JWH-030".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.