| J. Wayne Streilein | |
| Birth Date: | June 19, 1935 |
| Birth Place: | Johnstown, Pennsylvania |
| Death Place: | Boston, Massachusetts |
| Fields: | Immunology Ophthalmology Dermatology |
| Workplaces: | Harvard Medical School |
| Alma Mater: | University of Pennsylvania School of Medicine, MD, 1960 |
| Known For: | "The Father of Modern Ocular Immunology" |
J. Wayne Streilein (Johnstown, Pennsylvania, June 19, 1935 – March 15, 2004)[1] was a scientist whose main area of research was the ocular immune system.[2] He is known particularly for studying the mechanisms that keep the cornea avascular despite the inflammatory and other stimuli that usually promote small blood vessel ingrowth; these peculiar corneal mechanisms provide the basis for what is known as the "corneal antiangiogenic privilege".[3]