| Journal of Clinical Investigation | |
| Cover: | Journal_of_Clinical_Investigation_sample_cover_image_(August_2015).jpg |
| Editor: | Elizabeth M. McNally |
| Discipline: | Biomedicine |
| Abbreviation: | J. Clin. Investig. |
| Nlm: | J Clin Invest |
| Publisher: | American Society for Clinical Investigation |
| Country: | United States |
| Frequency: | Bimonthly |
| History: | 1924-present |
| Openaccess: | Hybrid |
| Impact: | 13.3 |
| Impact-Year: | 2023 |
| Website: | http://www.jci.org/ |
| Link1: | https://www.jci.org/current |
| Link1-Name: | Online access |
| Link2: | http://www.jci.org/archive |
| Link2-Name: | Online archive |
| Oclc: | 01445593 |
| Lccn: | 27010044 |
| Coden: | JCINAO |
| Issn: | 0021-9738 |
| Eissn: | 1558-8238 |
The Journal of Clinical Investigation (JCI) is a twice-monthly peer-reviewed medical journal covering biomedical research. It was established in 1924 and is published by the American Society for Clinical Investigation, one of the oldest and most respected medical honor societies in the United States. Articles focus on the mechanisms of disease, with an emphasis on basic research, early-stage clinical studies in humans, and new research tools and techniques. The journal also publishes reviews in edited series or as stand-alone articles, commentaries on research, editorials, and feature items. The editor-in-chief is Elizabeth M. McNally (Northwestern University).
The journal is abstracted and indexed in:
The following persons have been editor-in-chief of the journal:
The following articles have received the most citations, according to Scopus: