| Istmina | |
| Settlement Type: | Municipality and city |
| Mapsize: | 250px |
| Pushpin Mapsize: | 300 |
| Pushpin Map Caption: | Location in Colombia |
| Subdivision Type: | Country |
| Subdivision Name: |  Colombia |
| Subdivision Type1: | Department |
| Subdivision Name1: | Choco Department |
| Leader Title: | Mayor |
| Leader Name: | Arbey Pino |
| Established Title: | Founded |
| Established Date: | March 8, 1834 |
| Area Total Km2: | 1880 |
| Area Urban Km2: | 3.05 |
| Population As Of: | 2018 census |
| Population Footnotes: | [1] |
| Population Total: | 30742 |
| Population Density Km2: | auto |
| Population Urban: | 22258 |
| Population Density Urban Km2: | auto |
| Timezone: | Colombia Standard Time |
| Utc Offset: | -5 |
| Elevation M: | 65 |
| Elevation Ft: | 213.3 |
Istmina is a small city and municipality in the Chocó Department, Colombia. The city of Istmina was founded in 1834 by Juan Nepomuceno Mosquera, initially with the name of San Pablo. The name was changed in 1903 to Istmina, a contraction of isthmus and minas (mines), two characteristics of the area. The municipality covers 1880km2, with an average elevation of 79m (259feet), and an average temperature of 26.7C. Istmina is located 750NaN0 from the departmental capital, Quibdó.
Istmina has a very wet tropical rainforest climate (Af).