| Isso | |
| Official Name: | Comune di Isso |
| Coordinates: | 45.4833°N 55°W |
| Region: | Lombardy |
| Province: | Bergamo (BG) |
| Mayor: | Rocco Maccali |
| Area Total Km2: | 5.06 |
| Population Footnotes: | [1] |
| Population Total: | 637 |
| Population As Of: | 28 February 2017 |
| Population Demonym: | Issesi |
| Elevation M: | 104 |
| Postal Code: | 24040 |
| Area Code: | 0363 |
Isso (Bergamasque: Iss) is a comune (municipality) in the Province of Bergamo in the Italian region of Lombardy, located about 45km (28miles) east of Milan and about 25km (16miles) southeast of Bergamo.
Isso borders the following municipalities: Barbata, Camisano, Castel Gabbiano, Covo, Fara Olivana con Sola.