Isopiperitenol dehydrogenase explained

isopiperitenol dehydrogenase
Ec Number:	1.1.1.223
Cas Number:	96595-05-0
Go Code:	0018458

In enzymology, an isopiperitenol dehydrogenase is an enzyme that catalyzes the chemical reaction

(-)-trans-isopiperitenol + NAD⁺

\rightleftharpoons (-)-isopiperitenone + NADH + H⁺

Thus, the two substrates of this enzyme are (-)-trans-isopiperitenol and NAD⁺, whereas its 3 products are (-)-isopiperitenone, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is (-)-trans-isopiperitenol:NAD⁺ oxidoreductase. This enzyme participates in monoterpenoid biosynthesis.

References

• Kjonaas RB, Venkatachalam KV, Croteau R . 1985 . Metabolism of monoterpenes: oxidation of isopiperitenol to isopiperitenone, and subsequent isomerization to piperitenone by soluble enzyme preparations from peppermint (Mentha piperita) leaves . Arch. Biochem. Biophys. . 238 . 49 - 60 . 3885858 . 10.1016/0003-9861(85)90139-0 . 1 .